Aline Huguet-Lachon
Research Assistant
Titles and positions
Research Assistant
Expertises
- Molecular biology
- Histology
- Microscopy
- Animal experiments and behavioral tests
- Animal facility management
Presentation
I am working as research assistant in Geneviève Gourdon’s team, within the REDs – Repeat Expansions & Myotonic Dystrophy team. My project is to study the physiopathological consequences in newborns and to evaluate approaches therapeutics in mouse models.
Main publications
- Hernández-Hernández, O, Guiraud-Dogan, C, Sicot, G, Huguet, A, Luilier, S, Steidl, E et al.. Myotonic dystrophy CTG expansion affects synaptic vesicle proteins, neurotransmission and mouse behaviour. Brain. 2013;136 (Pt 3):957-70. doi: 10.1093/brain/aws367. PubMed PMID:23404338 PubMed Central PMC3580270.
- Huguet, A, Medja, F, Nicole, A, Vignaud, A, Guiraud-Dogan, C, Ferry, A et al.. Molecular, physiological, and motor performance defects in DMSXL mice carrying >1,000 CTG repeats from the human DM1 locus. PLoS Genet. 2012;8 (11):e1003043. doi: 10.1371/journal.pgen.1003043. PubMed PMID:23209425 PubMed Central PMC3510028.