Louise Benarroch
Chercheur Post-Doctorante
Titres
- Doctorat de Génétique, Université Paris Diderot (Paris VII)
- Chercheur Post-doctorant
Expertises
- Génétique
- Recherche de nouveaux gènes et de facteurs génétiques modificateurs
Présentation
Mon projet porte sur la recherche de facteurs génétique responsables de la variabilité phénotypique, inter- et intrafamiliale, observable dans les laminopathies du muscle strié.
Principales publications
- Bertrand, AT, Brull, A, Azibani, F, Benarroch, L, Chikhaoui, K, Stewart, CL et al.. Lamin A/C Assembly Defects in LMNA-Congenital Muscular Dystrophy Is Responsible for the Increased Severity of the Disease Compared with Emery-Dreifuss Muscular Dystrophy. Cells. 2020;9 (4):. doi: 10.3390/cells9040844. PubMed PMID:32244403 PubMed Central PMC7226786.
- Benarroch, L, Bonne, G, Rivier, F, Hamroun, D. The 2020 version of the gene table of neuromuscular disorders (nuclear genome). Neuromuscul Disord. 2019;29 (12):980-1018. doi: 10.1016/j.nmd.2019.10.010. PubMed PMID:31791870 .
- Antunes, JC, Benarroch, L, Moraes, FC, Juenet, M, Gross, MS, Aubart, M et al.. Core-Shell Polymer-Based Nanoparticles Deliver miR-155-5p to Endothelial Cells. Mol Ther Nucleic Acids. 2019;17 :210-222. doi: 10.1016/j.omtn.2019.05.016. PubMed PMID:31265949 PubMed Central PMC6610682.
- Benarroch, L, Aubart, M, Gross, MS, Arnaud, P, Hanna, N, Jondeau, G et al.. Reference Expression Profile of Three FBN1 Transcript Isoforms and Their Association with Clinical Variability in Marfan Syndrome. Genes (Basel). 2019;10 (2):. doi: 10.3390/genes10020128. PubMed PMID:30754709 PubMed Central PMC6409622.
- Arnaud, P, Hanna, N, Benarroch, L, Aubart, M, Bal, L, Bouvagnet, P et al.. Genetic diversity and pathogenic variants as possible predictors of severity in a French sample of nonsyndromic heritable thoracic aortic aneurysms and dissections (nshTAAD). Genet Med. 2019;21 (9):2015-2024. doi: 10.1038/s41436-019-0444-y. PubMed PMID:30739908 .
- Benarroch, L, Aubart, M, Gross, MS, Jacob, MP, Arnaud, P, Hanna, N et al.. Marfan Syndrome Variability: Investigation of the Roles of Sarcolipin and Calcium as Potential Transregulator of FBN1 Expression. Genes (Basel). 2018;9 (9):. doi: 10.3390/genes9090421. PubMed PMID:30134586 PubMed Central PMC6162465.
- Aubart, M, Gazal, S, Arnaud, P, Benarroch, L, Gross, MS, Buratti, J et al.. Association of modifiers and other genetic factors explain Marfan syndrome clinical variability. Eur J Hum Genet. 2018;26 (12):1759-1772. doi: 10.1038/s41431-018-0164-9. PubMed PMID:30087447 PubMed Central PMC6244213.
- Benarroch, L, Kowalchuk, C, Wilson, V, Teo, C, Guenette, M, Chintoh, A et al.. Atypical antipsychotics and effects on feeding: from mice to men. Psychopharmacology (Berl). 2016;233 (14):2629-53. doi: 10.1007/s00213-016-4324-8. PubMed PMID:27251130 .