Myopathies inflammatoires & thérapies innovantes ciblées
Les myosites sont des maladies auto-immunes qui affectent les muscles et sont souvent associées à des atteintes extra-musculaires (par exemple, la peau, les articulations ou les poumons). Les myosites constituent donc un groupe de maladies qui n’affectent que les muscles ou qui sont des maladies systémiques. Ces affections peuvent être spontanées ou déclenchées par le cancer et/ou les traitements (par exemple, les médicaments hypocholestérolémiants ou les immunothérapies anticancéreuses). Il s’agit de maladies graves qui peuvent entraîner un handicap, voire mettre en jeu le pronostic vital. Le traitement associe généralement des corticostéroïdes et des immunosuppresseurs, mais sans approches ciblées et sans tenir compte des spécificités des sous-groupes de myosites.
Notre objectif est d’améliorer la prise en charge diagnostique et thérapeutique des myosites.
Notre approche est translationnelle : du laboratoire au patient et du patient au laboratoire.
Notre équipe est composée de médecins/chercheurs experts en myosite, d’ingénieurs de recherche, de biostaticiens, de doctorants et de post-doctorants.
Nous avons créé une biobanque contenant des échantillons biologiques de plus de 1 500 patients atteints de myosite, ainsi que des données médicales associées. Dans notre laboratoire, nous disposons d’un environnement de recherche exceptionnel axé sur les maladies musculaires et auto-immunes, permettant l’analyse d’échantillons et l’expérimentation in vitro, notamment à l’aide de modèles de culture de cellules musculaires, pour atteindre nos objectifs.
Nos recherches s’articulent autour de trois axes principaux :
(i) définir des groupes de patients homogènes, (ii) analyser les mécanismes physiopathologiques au niveau des tissus, et (iii) développer des outils diagnostiques et thérapeutiques innovants.
1- Cadre nosologique : Identifier ses adversaires
Comme préalable à tout travail de recherche, il est nécessaire de définir des groupes de patients homogènes avec des mécanismes pathologiques communs.
Au cours des 10 dernières années, nous avons été à l’avant-garde de la révision des critères diagnostiques internationaux des principaux sous-groupes de myosites (dermatomyosite, myopathie nécrosante à médiation immunitaire et syndrome des anti-synthétases). Nous avons démontré, avec d’autres, le rôle crucial des anticorps spécifiques de la myosite pour diagnostiquer et classer les patients atteints de myosite dans des groupes homogènes et nous avons organisé une conférence de consensus sur les méthodes de détection des auto-anticorps spécifiques de la myosite (ENMC 2021 criteria). Nous avons également contribué à l’atelier affinant les critères de diagnostic de la myosite à corps inclus (ENMC 2023 criteria).
Nous avons également été les premiers à décrire un nouveau sous-groupe de myosites induites par les inhibiteurs du point de contrôle immunitaire (ICI), dont l’utilisation représente une avancée majeure dans le traitement du cancer. Nous avons rapporté la plus grande série de myosites induites par les ICI, démontrant que la maladie diffère de la myosite spontanée en termes de phénotype et de taux de mortalité élevé. En effet, ces dernières années, une nouvelle forme de myosite est apparue, combinant des manifestations musculaires et cardiaques sévères. Naturellement, notre équipe s’est enrichie d’un cardiologue de renommée mondiale (Pr Salem) spécialiste de la toxicité cardiaque des médicaments anticancéreux et des myocardites induites par l’immunothérapie anti-tumorale.
2- Clarifier le pathomécanisme : Identifier les faiblesses de l’adversaire
Nous avons contribué à démontrer le rôle pathogène des auto-anticorps dans les myosites, en particulier dans la forme la plus invalidante, la myopathie nécrosante à médiation immunitaire. Nous avons également été pionniers dans la démonstration du rôle pathogène de l’interféron de type I dans la dermatomyosite.
Ces études nous ont amenés à analyser de près les caractéristiques de l’inflammation musculaire dans les tissus et, plus important encore, son effet sur les fibres musculaires.
Pour améliorer notre compréhension, nous avons dû développer et apprendre à utiliser des outils de séquençage de l’ARN au niveau d’un seul noyau ou d’une seule cellule, en utilisant des tissus digérés par voie enzymatique, mais aussi en préservant l’architecture des tissus (transcriptomique spatiale) afin d’analyser les interactions cellulaires. Ces nombreuses données moléculaires doivent être validées au niveau des protéines. C’est pourquoi nous avons mis en place des analyses d’imagerie multiplex utilisant la cytométrie de masse par imagerie (Hyperion®) ou menons des collaborations internationales pour des analyses de spectrométrie de masse.
Ces études nous ont permis de comprendre les mécanismes physiopathologiques de la myosite induite par l’immunothérapie, mettant en évidence le rôle important des cellules immunitaires résidentes dans le muscle.
Ces techniques nous ont également permis de démontrer l’importance des cellules résidentes non inflammatoires du tissu musculaire dans les mécanismes pathologiques et leur impact sur la régénération des cellules musculaires. Ces résultats nous amènent à analyser l’effet de l’inflammation sur le microenvironnement musculaire en testant des hypothèses à l’aide de modèles de culture 3D.
3- Développer une nouvelle stratégie thérapeutique : Vaincre son ennemi
Du laboratoire, nous retournons vers les patients pour leur proposer des solutions thérapeutiques.
Au cours des 10 dernières années, nos recherches ont débouché sur des essais cliniques contrôlés innovants (académiques ou industriels) pour chaque sous-groupe de myosites : myosites à inclusions, myopathies auto-immunes nécrosantes, syndrome des anti-synthétases, dermatomyosites. Par exemple, dans la dermatomyosite, des approches anti-interféron utilisant des inhibiteurs de JAK sont testées dans un essai contrôlé randomisé (PHRC 2018 ; PI Y. Allenbach).
Les études que nous avons menées ont également conduit à des développements à l’étranger, comme l’essai international de phase III testant la rapamycine dans la myosite à corps inclus (NCT04789070).
Parmi les dernières avancées sur lesquelles nous travaillons, nous proposons une thérapie innovante pour traiter les complications musculaires et cardiaques de l’immunothérapie, ainsi que des études en médecine régénérative par thérapie cellulaire pour la myosite à inclusions.
Nous avons récemment proposé de restaurer la force musculaire en utilisant la thérapie cellulaire avec la fraction vasculaire stromale (riche en cellules souches). Cet extrait cellulaire obtenu à partir du tissu adipeux peut se différencier en plusieurs lignées, dont le tissu musculaire. Nous avons obtenu une subvention (PHRC-N 2018 ; NCT05032131 PI O. Benveniste) pour mener un essai clinique de phase I afin de tester l’effet de l’injection à des patients atteints de myosite à bras d’inclusion non dominante de leurs cellules autologues de fraction vasculaire stromale obtenues à partir de tissu adipeux (après liposuccion).
Nous avons montré que l’Ig CTLA4 (Abatacept) peut aider les patients atteints de myosite et de myocardite sévères concomitantes (Salem 2023). Un essai thérapeutique est actuellement en cours (NCT05195645, PI JE Salem) pour tester l’Abatacept dans un ECR pour les patients atteints d’irAE sévère.
Contacts :
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Articles dans une revue
- Amélie Bourhis, Marie Robin, Stéphanie Nguyen, Arnaud Uguen, Patrice Hemon, et al.. Myopathy related to chronic Graft‐Versus‐Host Disease: From clinic to histological & immunological characterization by imaging mass cytometry. American Journal of Hematology, 2024, ⟨10.1002/ajh.27294⟩. ⟨hal-04574048⟩
- Charlotte Fenioux, Baptiste Abbar, Samia Boussouar, Marie Bretagne, John Power, et al.. Publisher Correction: Thymus alterations and susceptibility to immune checkpoint inhibitor myocarditis. Nature Medicine, 2024, ⟨10.1038/s41591-023-02771-0⟩. ⟨hal-04414859⟩
- Charlotte Fenioux, Baptiste Abbar, Samia Boussouar, Marie Bretagne, John Power, et al.. Thymus alterations and susceptibility to immune checkpoint inhibitor myocarditis. Nature Medicine, 2023, 29 (12), pp.3100-3110. ⟨10.1038/s41591-023-02591-2⟩. ⟨hal-04510220⟩
- Luce Barbat Du Closel, Nathalie Bonello-Palot, Yann Pereon, Andoni Echaniz-Laguna, Jean Philippe Camdessanche, et al.. Clinical and electrophysiological characteristics of women with X-linked Charcot-Marie-Tooth disease. European Journal of Neurology, 2023, 30 (10), pp.3265-3276. ⟨10.1111/ene.15937⟩. ⟨hal-04254200⟩
- Lorenz H. Lehmann, Markus B. Heckmann, Guillaume Bailly, Daniel Finke, Adrien Procureur, et al.. Cardiomuscular biomarkers in the diagnosis and prognostication of immune checkpoint Inhibitor myocarditis. Circulation, 2023, 148 (6), pp.473-486. ⟨10.1161/CIRCULATIONAHA.123.062405⟩. ⟨hal-04573185⟩
- Joe-Elie Salem, Marie Bretagne, Baptiste Abbar, Sarah Leonard-Louis, Stéphane Ederhy, et al.. Abatacept/Ruxolitinib and Screening for Concomitant Respiratory Muscle Failure to Mitigate Fatality of Immune-Checkpoint Inhibitor Myocarditis. Cancer Discovery, 2023, 13 (5), pp.1100-1115. ⟨10.1158/2159-8290.CD-22-1180⟩. ⟨hal-04578810⟩
- Tanya Stojkovic, Marion Masingue, Helène Turmel, Marianne Hezode-Arzel, Anthony Béhin, et al.. Diagnostic yield of a practical electrodiagnostic protocol discriminating between different congenital myasthenic syndromes. Neuromuscular Disorders, 2022, 32 (11-12), pp.870-878. ⟨10.1016/j.nmd.2022.10.001⟩. ⟨hal-04074000⟩
- Océane Landon-Cardinal, Perrine Guillaume-Jugnot, Ségolène Toquet, Nabiha Sbeih, Aude Rigolet, et al.. JAK inhibitors for the treatment of adult dermatomyositis: A pilot study. Journal of The American Academy of Dermatology, 2022, ⟨10.1016/j.jaad.2022.10.055⟩. ⟨hal-03996988⟩
- Alexandrine Mahoudeau, Céline Anquetil, Nozomu Tawara, Hossein Khademian, Damien Amelin, et al.. Myostatin in idiopathic inflammatory myopathies: Serum assessment and disease activity. Neuropathology and Applied Neurobiology, 2022, ⟨10.1111/nan.12849⟩. ⟨hal-03830849⟩
- Debora Pehl, Corinna Preuße, Yves Allenbach, Olivier Benveniste, Philipp Dittert, et al.. Eosinophilic fasciitis (Shulman syndrome)—recognition of the histological spectrum allows for new insights into possible pathomechanisms. Rheumatology, 2022, ⟨10.1093/rheumatology/keac526⟩. ⟨hal-03830836⟩
- Paul Breillat, Kuberaka Mariampillai, Paul Legendre, Pauline Martins, Bertrand Dunogue, et al.. Anti-PM-Scl antibodies–positive patients encompass three different groups with distinct prognoses. Rheumatology, 2022, ⟨10.1093/rheumatology/keac508⟩. ⟨hal-03830880⟩
- Sarah Julien, Douangsone Vadysirisack, Camil Sayegh, Sharan Ragunathan, Yalan Tang, et al.. Prevention of Anti-HMGCR Immune-Mediated Necrotising Myopathy by C5 Complement Inhibition in a Humanised Mouse Model. Biomedicines, 2022, 10 (8), pp.2036. ⟨10.3390/biomedicines10082036⟩. ⟨hal-03830885⟩
- Corinna Preuße, Barbara Paesler, Christopher Nelke, Derya Cengiz, Thomas Müntefering, et al.. Skeletal muscle provides the immunological micro-milieu for specific plasma cells in anti-synthetase syndrome-associated myositis. Acta Neuropathologica, 2022, 144 (2), pp.353-372. ⟨10.1007/s00401-022-02438-z⟩. ⟨hal-03830925⟩
- Jan Damoiseaux, Andrew Mammen, Yves Piette, Olivier Benveniste, Yves Allenbach. 256th ENMC international workshop: Myositis specific and associated autoantibodies (MSA-ab): Amsterdam, The Netherlands, 8-10 October 2021. Neuromuscular Disorders, 2022, 32 (7), pp.594-608. ⟨10.1016/j.nmd.2022.05.011⟩. ⟨hal-03830916⟩
- Antoine Soulages, Thierry Maisonobe, Pascal Auzou, Antoine Petit, Yves Allenbach, et al.. Peripheral neuropathy and livedoid vasculopathy. Journal of Neurology, 2022, 269 (7), pp.3779-3788. ⟨10.1007/s00415-022-11007-z⟩. ⟨hal-03832490⟩
- Corinna Preusse, Theodore Marteau, Norina Fischer, Andreas Hentschel, Albert Sickmann, et al.. Endoplasmic reticulum‐stress and unfolded protein response‐activation in immune‐mediated necrotizing myopathy. Brain Pathology, 2022, ⟨10.1111/bpa.13084⟩. ⟨hal-03830912⟩
- Caoilfhionn Connolly, Lotta Plomp, Julie Paik, Yves Allenbach. Possible future avenues for myositis therapeutics: DM, IMNM and IBM. Best Practice and Research: Clinical Rheumatology, 2022, 36 (2), pp.101762. ⟨10.1016/j.berh.2022.101762⟩. ⟨hal-03832475⟩
- Pierre Bay, Marc Pineton de Chambrun, Antoine Roux, Vincent Bunel, Alain Combes, et al.. Extracorporeal life support allows lung transplant in anti-MDA5+ rapidly progressive interstitial lung disease. European Respiratory Journal, 2022, 59 (5), pp.2102968. ⟨10.1183/13993003.02968-2021⟩. ⟨hal-03832484⟩
- Amandine Laporte, Kubéraka Mariampillai, Yves Allenbach, Nicoletta Pasi, Victoria Donciu, et al.. Idiopathic inflammatory myopathies: CT characteristics of interstitial lung disease and their association(s) with myositis-specific autoantibodies. European Radiology, 2022, 32 (5), pp.3480-3489. ⟨10.1007/s00330-021-08411-w⟩. ⟨hal-03830934⟩
- Lee Nguyen, Marie Bretagne, Jennifer Arrondeau, Noel Zahr, Stephane Ederhy, et al.. Reversal of immune-checkpoint inhibitor fulminant myocarditis using personalized-dose-adjusted abatacept and ruxolitinib: proof of concept. Journal for Immunotherapy of Cancer, 2022, 10 (4), pp.e004699. ⟨10.1136/jitc-2022-004699⟩. ⟨hal-04002766⟩
- Lee Nguyen, Marie Bretagne, Jennifer Arrondeau, Noel Zahr, Stephane Ederhy, et al.. Reversal of immune-checkpoint inhibitor fulminant myocarditis using personalized-dose-adjusted abatacept and ruxolitinib: proof of concept. Journal for Immunotherapy of Cancer, 2022, 10 (4), pp.e004699. ⟨10.1136/jitc-2022-004699⟩. ⟨hal-03832478⟩
- Wladimir Mauhin, Abdellah Tebani, Damien Amelin, Lenaig Abily-Donval, Foudil Lamari, et al.. Sphingosine-1-Phosphate Levels Are Higher in Male Patients with Non-Classic Fabry Disease. Journal of Clinical Medicine, 2022, 11 (5), pp.1233. ⟨10.3390/jcm11051233⟩. ⟨hal-03830929⟩
- Stéphane Ederhy, Perrine Devos, Bruno Pinna, Elisa Funck-Brentano, Baptiste Abbar, et al.. 8 F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography imaging for the diagnosis of immune checkpoint inhibitors associated myocarditis. Archives of cardiovascular diseases, 2022, ⟨10.1016/j.acvd.2021.12.001⟩. ⟨hal-03561783⟩
- Carolien Bonroy, Yves Piette, Yves Allenbach, Xavier Bossuyt, Jan Damoiseaux. Positioning of myositis-specific and associated autoantibody (MSA/MAA) testing in disease criteria and routine diagnostic work-up. Journal of Translational Autoimmunity, 2022, 5, pp.100148. ⟨10.1016/j.jtauto.2022.100148⟩. ⟨hal-03832479⟩
- Joe-Elie Salem, Nadjib Hammoudi, Bruno Pinna, Stephane Ederhy, Antonin Lamazière, et al.. Echocardiography and renin-aldosterone interplay as predictors of death in COVID-19. Archives of cardiovascular diseases, In press, ⟨10.1016/j.acvd.2021.11.006⟩. ⟨hal-03572401⟩
- Xavier Mariette, Olivier Hermine, Pierre-Louis Tharaux, Matthieu Resche-Rigon, Raphael Porcher, et al.. Sarilumab in adults hospitalised with moderate-to-severe COVID-19 pneumonia (CORIMUNO-SARI-1): An open-label randomised controlled trial. The Lancet Rheumatology, 2022, 4 (1), pp.e24-e32. ⟨10.1016/S2665-9913(21)00315-5⟩. ⟨hal-03783213⟩
- Pierre Bay, Marc de Chambrun, Vincent Rothstein, Matthiéu Mahevas, Nicolas de Prost, et al.. Efficacy of plasma exchange in patients with anti-MDA5 rapidly progressive interstitial lung disease. Journal of Autoimmunity, 2022, 133, ⟨10.1016/j.jaut.2022.102941⟩. ⟨hal-03950145⟩
- Gorka Fernández-Eulate, Rabab Debs, Thierry Maisonobe, Philippe Latour, Fleur Cohen-Aubart, et al.. Sjögren syndrome and RFC1-CANVAS sensory ganglionopathy: co-occurrence or misdiagnosis?. Journal of Neurology, 2022, ⟨10.1007/s00415-022-11382-7⟩. ⟨hal-03830863⟩
- Franck Phan, Samia Boussouar, Olivier Lucidarme, Mohamed Zarai, Joe-Elie Salem, et al.. Cardiac adipose tissue volume and IL-6 level at admission are complementary predictors of severity and short-term mortality in COVID-19 diabetic patients. Cardiovascular Diabetology, 2021, 20, pp.165. ⟨10.1186/s12933-021-01327-1⟩. ⟨hal-03346419⟩
- Bonny Rockette-Wagner, Didem Saygin, Siamak Moghadam-Kia, Chester Oddis, Océane Landon-Cardinal, et al.. Reliability, validity and responsiveness of physical activity monitors in patients with inflammatory myopathy. Rheumatology, 2021, 60 (12), pp.5713-5723. ⟨10.1093/rheumatology/keab236⟩. ⟨hal-03832520⟩
- Nadège Cordel, Céline Derambure, Sophie Coutant, Xavier Mariette, Denis Jullien, et al.. TRIM33 gene somatic mutations identified by next generation sequencing in neoplasms of patients with anti-TIF1γ positive cancer-associated dermatomyositis. Rheumatology, 2021, 60 (12), pp.5863-5867. ⟨10.1093/rheumatology/keab260⟩. ⟨hal-03667247⟩
- Helena Costa-Verdera, Fanny Collaud, Christopher R Riling, Pauline Sellier, Jayme M L Nordin, et al.. Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates. Nature Communications, 2021, 12 (1), pp.6393. ⟨10.1038/s41467-021-26744-4⟩. ⟨hal-03449262⟩
- John R Power, Joachim Alexandre, Arrush Choudhary, Benay Ozbay, Salim Hayek, et al.. Electrocardiographic Manifestations of Immune Checkpoint Inhibitor Myocarditis. Circulation, 2021, 144 (18), pp.1521-1523. ⟨10.1161/CIRCULATIONAHA.121.055816⟩. ⟨hal-03414602⟩
- Rocio Nur Villar-Quiles, Norma B Romero, Stojkovic Tanya. Dystrophie musculaire liée à des mutations du gène JAG2 : l'importance du diagnostic différentiel. Médecine/Sciences, 2021, 37, pp.40-43. ⟨10.1051/medsci/2021191⟩. ⟨hal-03475173⟩
- Lorenz Lehmann, Jennifer Cautela, Nicolas Palaskas, Alan Baik, Wouter Meijers, et al.. Clinical Strategy for the Diagnosis and Treatment of Immune Checkpoint Inhibitor–Associated Myocarditis. JAMA Cardiology, 2021, 6 (11), pp.1329. ⟨10.1001/jamacardio.2021.2241⟩. ⟨hal-03654644⟩
- Antoine Marchiset, Mathilde Neuville, Guillaume Voiriot, Julien de Wolf, Matthieu Glorion, et al.. High-Emergency Lung Transplantation for Interstitial Lung Disease Associated With Anti-MDA5 Dermatomyositis: A Case Report. Transplantation Proceedings, 2021, 53 (8), pp.2613-2615. ⟨10.1016/j.transproceed.2021.08.012⟩. ⟨hal-04463966⟩
- Antoine Marchiset, Mathilde Neuville, Guillaume Voiriot, Julien de Wolf, Matthieu Glorion, et al.. High-Emergency Lung Transplantation for Interstitial Lung Disease Associated With Anti-MDA5 Dermatomyositis: A Case Report. Transplantation Proceedings, 2021, 53 (8), pp.2613-2615. ⟨10.1016/j.transproceed.2021.08.012⟩. ⟨hal-03832502⟩
- Marc Pawlitzki, Christopher Nelke, Leoni Rolfes, Rebecca Hasseli, Stylianos Tomaras, et al.. NK Cell Patterns in Idiopathic Inflammatory Myopathies with Pulmonary Affection. Cells, 2021, 10 (10), pp.2551. ⟨10.3390/cells10102551⟩. ⟨hal-03369634⟩
- Franklin Ducatez, Wladimir Mauhin, Agnès Boullier, Carine Pilon, Tony Pereira, et al.. Parsing Fabry Disease Metabolic Plasticity Using Metabolomics. Journal of Personalized Medicine, 2021, 11 (9), pp.898. ⟨10.3390/jpm11090898⟩. ⟨hal-03366297⟩
- B. Lioger, C. Le Pendu, W. Mounfaloti, Yves Allenbach. [Rhabdomyolysis and anemia in a 25 year-old man].. La Revue de Médecine Interne, 2021, 42 (9), pp.669-671. ⟨10.1016/j.revmed.2021.08.007⟩. ⟨hal-03832510⟩
- Marion Quirins, Marie Théaudin, Fleur Cohen-Aubart, Alain Créange, Luc Mouthon, et al.. Nonsystemic vasculitic neuropathy: Presentation and long-term outcome from a French cohort of 50 patients. Autoimmunity Reviews, 2021, 20 (8), pp.102874. ⟨10.1016/j.autrev.2021.102874⟩. ⟨hal-03830977⟩
- Noël Zahr, Saik Urien, Benoit Llopis, Valérie Pourcher, Olivier Paccoud, et al.. Pharmacokinetics and pharmacodynamics of hydroxychloroquine in hospitalized patients with COVID-19. Therapies, 2021, 76 (4), pp.285-295. ⟨10.1016/j.therap.2021.01.056⟩. ⟨hal-04073526⟩
- Harmen Reyngoudt, Benjamin Marty, Jean-Marc Boisserie, Julien Le Louër, Cedi Koumako, et al.. Global versus individual muscle segmentation to assess quantitative MRI-based fat fraction changes in neuromuscular diseases. European Radiology, 2021, 31 (6), pp.4264-4276. ⟨10.1007/s00330-020-07487-0⟩. ⟨hal-03830984⟩
- François Fer, Y. Allenbach, Olivier Benveniste. La revue de médecine interne Myosites: de la classification au diagnostic. La Revue de Médecine Interne, 2021, 42 (6), pp.392-400. ⟨10.1016/j.revmed.2020.10.379⟩. ⟨hal-03577137⟩
- Nguyen Thi Huong, Rocio-Nur Villar-Quiles, Van Thuy Le, Sarah Leonard-Louis, Lilia Laddada, et al.. Leukoencephalopathy and conduction blocks in PLEKHG5-associated intermediate CMT disease. Neuromuscular Disorders, 2021, ⟨10.1016/j.nmd.2021.06.004⟩. ⟨hal-03285057⟩
- Marion Peyre, Noel Zahr, Quentin Riller, Fleur Cohen-Aubart, Yves Allenbach, et al.. Mycophenolic acid area under the curve in patients with inflammatory myopathies. Rheumatology, 2021, 60 (6), pp.3026-3028. ⟨10.1093/rheumatology/keab167⟩. ⟨hal-03830972⟩
- Charlotte Fenioux, Yves Allenbach, Aurore Vozy, Joe-Élie Salem, Georgina Maalouf, et al.. Comparaison des caractéristiques et des pronostics des patients avec et sans cancer actif hospitalisés pour une infection à SARS-CoV-2. Bulletin du Cancer, 2021, 108 (6), pp.581-588. ⟨10.1016/j.bulcan.2021.03.004⟩. ⟨hal-03830953⟩
- A Nguyen, Y Repesse, M Ebbo, Y Allenbach, Olivier Benveniste, et al.. IVIg increases interleukin-11 levels, which in turn contribute to increased platelets, VWF and FVIII in mice and humans. Clinical and Experimental Immunology, 2021, 204 (2), pp.258-266. ⟨10.1111/cei.13580⟩. ⟨hal-03830962⟩
- Loïs Bolko, Wei Jiang, Nozomu Tawara, Océane Landon-Cardinal, Céline Anquetil, et al.. The role of interferons type I, II and III in myositis: A review. Brain Pathology, 2021, 31 (3), pp.e12955. ⟨10.1111/bpa.12955⟩. ⟨hal-03242856⟩
- Corinna Preusse, Pascale Eede, Lucie Heinzeling, Kiara Freitag, Randi Koll, et al.. NanoString technology distinguishes anti‐TIF‐1γ + from anti‐Mi‐2 + dermatomyositis patients. Brain Pathology, 2021, 31 (3), ⟨10.1111/bpa.12957⟩. ⟨hal-03244148⟩
- Samuel Malartre, Damien Bachasson, Guillaume Mercy, Elissone Sarkis, Céline Anquetil, et al.. MRI and muscle imaging for idiopathic inflammatory myopathies. Brain Pathology, 2021, 31 (3), pp.e12954. ⟨10.1111/bpa.12954⟩. ⟨hal-03242994⟩
- Ségolène Toquet, Benjamin Granger, Yurdagul Uzunhan, Kubéraka Mariampillai, Hilario Nunes, et al.. The seasonality of Dermatomyositis associated with anti-MDA5 antibody: An argument for a respiratory viral trigger. Autoimmunity Reviews, 2021, 20 (4), pp.102788. ⟨10.1016/j.autrev.2021.102788⟩. ⟨hal-03830990⟩
- Anthony Amato, Michael Hanna, Pedro Machado, Umesh Badrising, Hector Chinoy, et al.. Efficacy and Safety of Bimagrumab in Sporadic Inclusion Body Myositis. Neurology, 2021, 96 (12), pp.e1595-e1607. ⟨10.1212/WNL.0000000000011626⟩. ⟨hal-03830946⟩
- Pierre-Louis Tharaux, Gilles Pialoux, Arthur Pavot, Xavier Mariette, Olivier Hermine, et al.. Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial. The Lancet Respiratory Medicine, 2021, 9 (3), pp.295-304. ⟨10.1016/S2213-2600(20)30556-7⟩. ⟨hal-03579180⟩
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- Arthur Geraud, Paul Gougis, Aurore Vozy, Celine Anquetil, Yves Allenbach, et al.. Clinical Pharmacology and Interplay of Immune Checkpoint Agents: A Yin-Yang Balance. Annual Review of Pharmacology and Toxicology, 2021, 61 (1), ⟨10.1146/annurev-pharmtox-022820-093805⟩. ⟨hal-02949235⟩
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- Douglas B Johnson, Joe-Elie Salem, Yves Allenbach, Aurore Vozy, Nicolas Brechot, et al.. Abatacept for Severe Immune Checkpoint Inhibitor–Associated Myocarditis. New England Journal of Medicine, 2019, 380 (24), pp.2377-2379. ⟨10.1056/NEJMc1901677⟩. ⟨hal-03155817⟩
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- Océane Landon-Cardinal, Yves Allenbach, Antoine Soulages, Aude Rigolet, Baptiste Hervier, et al.. Rituximab in the Treatment of Refractory Anti-HMGCR Immune-mediated Necrotizing Myopathy. Journal of Rheumatology, 2019, 46 (6), pp.623-627. ⟨10.3899/jrheum.171495⟩. ⟨hal-03523536⟩
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- Akinori Uruha, Yves Allenbach, J-L Charuel, Lucile Musset, Audrey Aussy, et al.. Diagnostic potential of sarcoplasmic myxovirus resistance protein A expression in subsets of dermatomyositis. Neuropathology and Applied Neurobiology, 2018, 45, pp.513 - 522. ⟨10.1111/nan.12519⟩. ⟨hal-03523507⟩
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- Damien Bachasson, Guillaume J.R. Dubois, Yves Allenbach, Olivier Benveniste, Jean-Yves Hogrel. Muscle Shear Wave Elastography in Inclusion Body Myositis: Feasibility, Reliability and Relationships with Muscle Impairments. Ultrasound in Medicine & Biology, 2018, 44 (7), pp.1423-1432. ⟨10.1016/j.ultrasmedbio.2018.03.026⟩. ⟨hal-01961259⟩
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- Yves Allenbach, Louiza Arouche-Delaperche, Corinna Preusse, Helena Radbruch, Gillian Butler-Browne, et al.. Necrosis in anti-SRP + and anti-HMGCR + myopathies. Neurology, 2018, 90 (6), pp.e507-e517. ⟨10.1212/WNL.0000000000004923⟩. ⟨hal-02377509⟩
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- Damien Bachasson, Océane Landon-Cardinal, Olivier Benveniste, Jean-Yves Hogrel, Yves Allenbach. Physical activity monitoring: A promising outcome measure in idiopathic inflammatory myopathies. Neurology, 2017, 89 (1), pp.101-103. ⟨10.1212/WNL.0000000000004061⟩. ⟨hal-03831217⟩
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- Nicolas Belhomme, Adel Maamar, Thomas Le Gallou, Marie-Christine Minot-Myhié, Antoine Larralde, et al.. Rare myopathy associated to MGUS, causing heart failure and responding to chemotherapy. Annals of Hematology, 2017, 96 (4), pp.695-696. ⟨10.1007/s00277-016-2916-3⟩. ⟨hal-01558317⟩
- Louiza Arouche-Delaperche, Yves Allenbach, Damien Amelin, Corinna Preusse, Vincent Mouly, et al.. Pathogenic role of anti-signal recognition protein and anti-3-Hydroxy-3-methylglutaryl-CoA reductase antibodies in necrotizing myopathies: Myofiber atrophy and impairment of muscle regeneration in necrotizing autoimmune myopathies. Annals of Neurology, 2017, 81 (4), pp.538-548. ⟨10.1002/ana.24902⟩. ⟨hal-02377502⟩
- Vadim Afanasiev, Sophie Demeret, Francis Bolgert, Bruno Eymard, Pascal Laforêt, et al.. Resistant myasthenia gravis and rituximab: A monocentric retrospective study of 28 patients. Neuromuscular Disorders, 2017, 27 (3), pp.251-258. ⟨10.1016/j.nmd.2016.12.004⟩. ⟨hal-03831207⟩
- Y. Allenbach, Olivier Benveniste, H-H. Goebel, W. Stenzel. Integrated classification of inflammatory myopathies. Neuropathology and Applied Neurobiology, 2017, 43 (1), pp.62-81. ⟨10.1111/nan.12380⟩. ⟨hal-03831213⟩
- R. Hardet, F. Mingozzi. Oral Tolerance: Another Reason to Eat Your Veggies!. Molecular Therapy, 2017, 25 (2), pp.311-313. ⟨10.1016/j.ymthe.2017.01.001⟩. ⟨hal-02880984⟩
- L. Gallay, N. Streichenberger, O. Benveniste, Y. Allenbach. Myosite focale : une maladie méconnue. La Revue de Médecine Interne, 2017, 38 (10), pp.679-684. ⟨10.1016/j.revmed.2017.06.015⟩. ⟨hal-01676079⟩
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- Akinori Uruha, Olivier Benveniste. Sporadic late-onset nemaline myopathy with monoclonal gammopathy of undetermined significance. Current Opinion in Neurology, 2017, 30 (5), pp.457 - 463. ⟨10.1097/WCO.0000000000000477⟩. ⟨hal-01684027⟩
- Margaret M. Mcgovern, Ruzan Avetisyan, Bernd-Jan Sanson, Olivier Lidove. Disease manifestations and burden of illness in patients with acid sphingomyelinase deficiency (ASMD). Orphanet Journal of Rare Diseases, 2017, 12, pp.41. ⟨10.1186/s13023-017-0572-x⟩. ⟨hal-01480359⟩
- Wladimir Mauhin, Kuberaka Mariampillai, Yves Allenbach, Jean-Luc Charuel, Lucile Musset, et al.. Anti-mitochondrial antibodies are not a hallmark of severity in idiopathic inflammatory myopathies. Joint Bone Spine, 2017, ⟨10.1016/j.jbspin.2017.04.004⟩. ⟨hal-01518320⟩
- Lucile Musset, Yves Allenbach, Olivier Benveniste, Olivier Boyer, Xavier Bossuyt, et al.. Anti-HMGCR antibodies as a biomarker for immune-mediated necrotizing myopathies: A history of statins and experience from a large international multi-center study. Autoimmunity Reviews, 2016, 15 (10), pp.983-993. ⟨10.1016/j.autrev.2016.07.023⟩. ⟨hal-02377492⟩
- Yves Allenbach, Jeremy Keraen, Anne-Marie Bouvier, Valérie Jooste, Nicolas Champtiaux, et al.. High risk of cancer in autoimmune necrotizing myopathies: usefulness of myositis specific antibody. Brain - A Journal of Neurology , 2016, 139 (8), pp.2131 - 2135. ⟨10.1093/brain/aww054⟩. ⟨hal-01409979⟩
- E. Hachulla, Olivier Benveniste, M. Hamidou, L. Mouthon, N. Schleinitz, et al.. High dose subcutaneous immunoglobulin for idiopathic inflammatory myopathies and dysimmune peripheral chronic neuropathies treatment: observational study of quality of life and tolerance. International Journal of Neuroscience, 2016, 127 (6), pp.516-523. ⟨10.1080/00207454.2016.1204544⟩. ⟨hal-03831224⟩
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- Yves Allenbach, Marguerite Guiguet, Aude Rigolet, Isabelle Marie, Eric Hachulla, et al.. Efficacy of Rituximab in Refractory Inflammatory Myopathies Associated with Anti- Synthetase Auto-Antibodies: An Open-Label, Phase II Trial. PLoS ONE, 2015, 10 (11), pp.e0133702. ⟨10.1371/journal.pone.0133702⟩. ⟨hal-01277958⟩
- Manuelle Viguier, Stéphanie Rist, François Aubin, Marie-Thérèse Leccia, Marie-Aleth Richard, et al.. Online Training on Skin Cancer Diagnosis in Rheumatologists: Results from a Nationwide Randomized Web-Based Survey. PLoS ONE, 2015, ⟨10.1371/journal.pone.0127564⟩. ⟨hal-01211398⟩
- Alain Meyer, Guillaume Lefevre, Guillaume Bierry, Aurélie Duval, Sébastien Ottaviani, et al.. In Antisynthetase Syndrome, ACPA Are Associated With Severe and Erosive Arthritis: An Overlapping Rheumatoid Arthritis and Antisynthetase Syndrome. Medicine, 2015, 94 (20), pp.e523. ⟨10.1097/MD.0000000000000523⟩. ⟨hal-01226438⟩
- Guillaume Lefèvre, Alain Meyer, David Launay, Irène Machelart, Michel Debandt, et al.. Seronegative polyarthritis revealing antisynthetase syndrome: a multicentre study of 40 patients. Rheumatology, 2015, 54 (5), pp.927-932. ⟨10.1093/rheumatology/keu404⟩. ⟨hal-02416117⟩
- Olivier Benveniste, Werner Stenzel, David Hilton-Jones, Marco Sandri, Olivier Boyer, et al.. Amyloid deposits and inflammatory infiltrates in sporadic inclusion body myositis: the inflammatory egg comes before the degenerative chicken. Acta Neuropathologica, 2015, 129 (5), pp.611-624. ⟨10.1007/s00401-015-1384-5⟩. ⟨hal-02377450⟩
- Maeva Ferrari, Karine Louati, Anne Miquel, Anthony Behin, Olivier Benveniste, et al.. Quickly progressive amyotrophy of the thigh: An unusual cause of rapid chondrolysis of the knee. Joint Bone Spine, 2015, 82 (3), pp.203-205. ⟨10.1016/j.jbspin.2014.12.013⟩. ⟨hal-01117107⟩
- Yves Allenbach, Wahiba Chaara, Michelle Rosenzwajg, Adrien Six, Nicolas Prevel, et al.. Th1 Response and Systemic Treg Deficiency in Inclusion Body Myositis. PLoS ONE, 2014, 9 (3), pp.e88788. ⟨10.1371/journal.pone.0088788⟩. ⟨hal-01344508⟩
- Laurent Drouot, Yves Allenbach, Fabienne Jouen, Jean-Luc Charuel, Jérémie Martinet, et al.. Exploring necrotizing autoimmune myopathies with a novel immunoassay for anti-3-hydroxy-3-methyl-glutaryl-CoA reductase autoantibodies.. Arthritis Research and Therapy, 2014, 16 (1), pp.R39. ⟨10.1186/ar4468⟩. ⟨inserm-00950634⟩
- Meenu Sharma, Yoland Schoindre, Pushpa Hegde, Chaitrali Saha, Mohan S Maddur, et al.. Intravenous immunoglobulin-induced IL-33 is insufficient to mediate basophil expansion in autoimmune patients. Scientific Reports, 2014, 4 (1), pp.5672. ⟨10.1038/srep05672⟩. ⟨hal-01358914⟩
- G. Couvrat-Desvergnes, A. Masseau, O. Benveniste, A. Bruel, B. Hervier, et al.. The spectrum of renal involvement in patients with inflammatory myopathies. Medicine (Baltimore), 2014, 93 (1), pp.33-41. ⟨10.1097/MD.0000000000000015⟩. ⟨hal-01859438⟩
- Marion Desdouits, Olivier Cassar, Thierry Maisonobe, Alexandra Desrames, Achille Aouba, et al.. HTLV-1-associated inflammatory myopathies: low proviral load and moderate inflammation in 13 patients from West Indies and West Africa.. Journal of Clinical Virology, 2013, 57 (1), pp.70-6. ⟨10.1016/j.jcv.2012.12.016⟩. ⟨pasteur-01370950⟩
- France Herson, Faycal Hentati, Aude Rigolet, Anthony Behin, Norma Beatriz Romero, et al.. A phase I trial of adeno-associated virus serotype 1-γ-sarcoglycan gene therapy for limb girdle muscular dystrophy type 2C. Brain - A Journal of Neurology , 2012, 135 (2), pp.483-492. ⟨10.1093/brain/awr342⟩. ⟨hal-02179399⟩
- V. Monteilhet, S. Saheb, Sylvie Boutin, C. Leborgne, P. Veron, et al.. A 10 patient case report on the impact of plasmapheresis upon neutralizing factors against adeno-associated virus (AAV) types 1, 2, 6, and 8. Molecular Therapy, 2011, 19 (11), pp.2084-91. ⟨10.1038/mt.2011.108⟩. ⟨hal-02881133⟩
- B. Hervier, Y. Uzunhan, Eric Hachulla, Olivier Benveniste, H. Nunes, et al.. Antisynthetase syndrome positive for anti-threonyl-tRNA synthetase (anti-PL7) antibodies.. European Respiratory Journal, 2011, 37 (3), pp.714-7. ⟨10.1183/09031936.00104310⟩. ⟨hal-00873290⟩
- Sandrine Larue, Thierry Maisonobe, Olivier Benveniste, Catherine Chapelon-Abric, Olivier Lidove, et al.. DISTAL MUSCLE INVOLVEMENT IN GRANULOMATOUS MYOSITIS CAN MIMIC INCLUSION BODY MYOSITIS. Journal of Neurology, Neurosurgery and Psychiatry, 2010, 82 (6), pp.674. ⟨10.1136/jnnp.2009.190751⟩. ⟨hal-00591161⟩
- Yves Allenbach, Sounkary Solly, Sylvie Grégoire, Odile Dubourg, Benoit Salomon, et al.. Role of regulatory T cells in a new mouse model of experimental autoimmune myositis.. American Journal of Pathology, 2009, 174 (3), pp.989-98. ⟨10.2353/ajpath.2009.080422⟩. ⟨hal-00420196⟩
- Philippe Morlat, Edwidge Pereira, Pascal Clayette, Nathalie Derreudre-Bosquet, Jean-Luc Ecobichon, et al.. Early evolution of plasma soluble TNF-alpha p75 receptor as a marker of progression in treated HIV-infected patients.. AIDS Research and Human Retroviruses, 2008, 24 (11), pp.1383-9. ⟨10.1089/aid.2007.0293⟩. ⟨inserm-00350155⟩
- Yohan Georges, Yves Allenbach, Xavier Ariza, Jean-Marc Campagne, Jordi Garcia. An Efficient, Stereoselective Approach to syn-1,2-Diols Protected as Cyclic Carbonates. Journal of Organic Chemistry, 2004, 69, pp.7387. ⟨10.1021/jo048985g⟩. ⟨hal-00165650⟩
Communications dans un congrès
- Olivier Benveniste. Refractory myositides.. XVIth UCLouvain Review Course on Systemic Rheumatic Diseases, Nov 2022, Bruxelles, Belgium. ⟨hal-03864159⟩
- Olivier Benveniste. Les myopathies inflammatoires en 2022 : de la physiopathologie aux traitements ciblés. 17ème Journées Scientifiques de la Société Tunisienne d’Immunologie, Nov 2022, Hammamet, Tunisie. ⟨hal-03864162⟩
- Yves Allenbach. Quoi de neuf dans la prise en charge des dermatomyosites à anti-MDA5 sévères ?. 13ième Journée du Muscle Inflammatoire, Sep 2022, Paris, France. ⟨hal-03835354⟩
- Yves Allenbach. 256th ENMC International Workshop: Myositis specific autoantibodies (MSAab). 13ième Journée Interdisciplinaire du Muscle Inflammatoire, Sep 2022, Paris, France. ⟨hal-03835350⟩
- Olivier Benveniste. Inflammatory Myopathies and Innovative Therapies. TMA’s Annual Patient Conference, Sep 2022, Orlando, United States. ⟨hal-03864169⟩
- Yves Allenbach. Acute ILD MdA5. 15th International Congress on lung transplantation, Sep 2022, Paris, France. ⟨hal-03834287⟩
- Yves Allenbach. Q/A with medical advisory board breakouts - myotoxicity. 2022 International Annual Patient Conference, Sep 2022, Orlando, United States. ⟨hal-03834288⟩
- Olivier Benveniste. Treatment Options for Idiopathic Inflammatory Myopathies. 17th International Congress on NeuroMuscular Diseases, Jul 2022, Bruxelles, Belgium. ⟨hal-03864178⟩
- P. Bay, M. Pineton de Chambrun, A. Roux, V. Bunel, A. Combes, et al.. L’assistance extracorporelle en bridge à la transplantation pulmonaire en urgence pour les patients avec une atteinte pulmonaire rapidement progressive d’une dermatomyosite anti-MDA5. 84ème congrès de la SNFMI, Jun 2022, Nantes, France. pp.A122, ⟨10.1016/j.revmed.2022.03.320⟩. ⟨hal-03834086⟩
- P. Bay, M. Pineton de Chambrun, V. Rothstein, M. Mahevas, A. Roux, et al.. Les échanges plasmatiques ne semblent pas être associés à un meilleur pronostic chez les patients avec une atteinte pulmonaire rapidement progressive d’une dermatomyosite anti-MDA5. 84ème congrès de la SNFMI, Jun 2022, Nantes, France. pp.A99-A100, ⟨10.1016/j.revmed.2022.03.288⟩. ⟨hal-03834088⟩
- Sami Mensi, Olivier Benveniste, Yves Allenbach. Use of 18-FDG PET-CT in idiopathic inflammatory myopathies, a retrospective series of 93 examinations. A tool with uncertain performances. 4th Global Conference on Myositis (GCOM 2022), Jun 2022, Prague, Czech Republic. ⟨hal-03834099⟩
- Olivier Benveniste. Inclusion Body Myositis in 2022: from physiopathogenesis to clinical trials. 4th Global Conference On Myositis,, Jun 2022, Prague, Czech Republic. ⟨hal-03864190⟩
- Lotta Plomp, Hortense Chassepot, Olivier Benveniste, Yves Allenbach. Immune checkpoint inhibitor -related myotoxicity: musculoskeletal and/or neuromuscular junction disorder?. 4th GLOBAL CONFERENCE ON MYOSITIS 2022 (GCOM 2022), Jun 2022, Prague, Czech Republic. ⟨hal-03834096⟩
- Yves Allenbach. Myositis triggered by checkpoint inhibitors. 4th Global Conference On Myositis (GCOM 2022), Jun 2022, Prague, Czech Republic. ⟨hal-03832584⟩
- Yves Allenbach. les syndromes antisynthétases et MDA5. 12e colloque fribourgeois de rhumatologie, Apr 2022, Fribourg, Suisse. ⟨hal-03835085⟩
- Ryan Hum, James Lilleker, Janine Lamb, William Ollier, Guochung Wang, et al.. P222 Clinical features of extra-muscular disease in dermatomyositis and anti-synthetase syndrome patients with skin involvement classified by presence of disease-specific autoantibodies: results from the EuroMyositis registry. British Society for Rheumatology Annual Conference, BSR 2022, Apr 2022, Glasgow, United Kingdom. ⟨10.1093/rheumatology/keac133.221⟩. ⟨hal-03831256⟩
- Abdellah Tebani, Franklin Ducatez, Wladimir Mauhin, Agnès Boullier, Carine Pilon, et al.. Dissecting Fabry disease biological plasticity using network-based metabolic phenotyping. WORLDSymposium™ 2022, Feb 2022, San diego, United States. pp.S118, ⟨10.1016/j.ymgme.2021.11.314⟩. ⟨hal-03831262⟩
- Pierre Bay, Marc Pineton de Chambrun, Vincent Rothstein, Matthieu Mahevas, Nicolas de Prost, et al.. Plasma exchange are not associated with better outcome in MDA5 rapidly-progressive interstitial lung disease. French Intensive Care Society International Congress 2022, 2022, paris, France. pp.54, ⟨10.1186/s13613-022-01016-6⟩. ⟨hal-03831253⟩
- K. Gourbeyre-Masson, O. Benveniste, B. Colombe, Yves Allenbach, N. Terzi, et al.. Profil et pronostic des myopathies inflammatoires en unité de soins intensifs: une étude rétrospective et multicentrique. 83ème congrès de la SNFMI, Dec 2021, Paris, France. pp.A265, ⟨10.1016/j.revmed.2021.10.203⟩. ⟨hal-03834072⟩
- L. Bolko, S. Louis-Leonard, L. Kanagaratnam, C. Pineau, C. Anquetil, et al.. Précision diagnostique de l’électroneuromyogramme dans les myosites. 83ème congrès de la SNFMI, Dec 2021, Paris, France. pp.A265-A266, ⟨10.1016/j.revmed.2021.10.204⟩. ⟨hal-03834082⟩
- A. Chaudier, Yves Allenbach, A. Mekinian, C. Richez, M.E. Truchetet, et al.. Tolérance et efficacité des thérapies ciblées prescrites dans des indications hors AMM au cours des maladies auto-immunes systémiques réfractaires : données des 100 premiers patients inclus dans le registre TATA (TArgeted Therapy in Auto-immune Diseases). 83e Congrès de la SNFMI, Dec 2021, Paris, France. pp.A407, ⟨10.1016/j.revmed.2021.10.119⟩. ⟨hal-03834090⟩
- Yves Allenbach, G. Mercy, J.F. Deux, F. Foissac, Y. Schoindre, et al.. Performances de l’IRM musculaire pour le diagnostic des myopathies auto-immunes : étude prospective multicentrique (DARWIM). 83ème congrès de la SNFMI, Dec 2021, Paris, France. pp.A266, ⟨10.1016/j.revmed.2021.10.205⟩. ⟨hal-03834081⟩
- S. Mensi, P. Daniel, D. Kharroubi, Yves Allenbach, A. Kas, et al.. Emploi de la TEP-TDM au 18-FDG dans les myopathies inflammatoires, description rétrospective sur une série de 93 examens, un outil aux performances encore incertaines. 83ème congrès de la SNFMI8, Dec 2021, Paris, France. pp.A266-A267, ⟨10.1016/j.revmed.2021.10.206⟩. ⟨hal-03834084⟩
- J. Demortier, M. Vautier, O. Chosidow, L. Gallay, D. Bessis, et al.. Dermatomyosite à anticorps anti-SAE: étude descriptive et comparative à un groupe de dermatomyosites SAE-négatives. 83ème congrès de la SNFMI, Dec 2021, Paris, France. pp.A264, ⟨10.1016/j.revmed.2021.10.202⟩. ⟨hal-03834077⟩
- S. Mensi, H. Chassepot, D. Kharroubi, L. Plomp, B. Abbar, et al.. Valeur diagnostique de la TEP-TDM au 18-FDG dans les myosites secondaires aux inhibiteurs de point de contrôle immunitaires. 83ème congrès de la SNFMI, Dec 2021, Paris, France. pp.A267-A268, ⟨10.1016/j.revmed.2021.10.207⟩. ⟨hal-03834079⟩
- H. Chassepot, L. Plomp, S. Mensi, D. Psimaras, M. Touat, et al.. Myotoxicité liée aux inhibiteurs de points de contrôle immunitaire: trouble de l’appareil musculaire et/ou de la jonction neuromusculaire?. 83ème congrès de la SNFMI, Dec 2021, Paris, France. pp.A269, ⟨10.1016/j.revmed.2021.10.209⟩. ⟨hal-03834073⟩
- P. Breillat, K. Mariampillai, P. Martins, P. Legendre, B. Dunogué, et al.. Spectre clinique et pronostic des connectivites à anti PM-Scl ; une étude multicentrique incluant 128 patients. 83ème congrès de la SNFMI, Dec 2021, Paris, France. pp.A91-A92, ⟨10.1016/j.revmed.2021.03.316⟩. ⟨hal-03834083⟩
- J.E. Gottenberg, A. Chaudier, Yves Allenbach, A. Mékinian, C. Richez, et al.. Tolérance et efficacité des thérapies ciblées prescrites hors AMM au cours des maladies auto-immunes systémiques réfractaires : données des 100 premiers patients inclus dans le registre TATA (TArgeted Therapy in Autoimmune Diseases). 34e Congrès français de la SFR, Dec 2021, Paris, France. pp.A54, ⟨10.1016/j.rhum.2021.10.081⟩. ⟨hal-03834093⟩
- Olivier Benveniste. Actual landscape of (auto-immune) inflammatory myopathies. Portuguese Congress of Neuromuscular Disorders, Oct 2021, NA, Portugal. ⟨hal-03831945⟩
- Olivier Benveniste. The Rapamycin Study for IBM. 2021 Muscle Study Group Scientific Annual Meeting, Oct 2021, NA, United States. ⟨hal-03831935⟩
- Yves Allenbach. Myosite et IRM musculaire. 13éme édition du JIMI (Journée Interdisciplinaire du Muscle Inflammatoire), Sep 2021, Paris, France. ⟨hal-03835505⟩
- Yves Allenbach. What's new in Myositis ?. German Rheumatology Congress (virtual), Sep 2021, Berlin, Germany. ⟨hal-03834281⟩
- Eveline Van Gompel, Catia Cerqueira, Begum Horuluoglu, Angeles Shunashy Galindo- Feria, Karine Chemin, et al.. Anti-MDA5 autoantibodies in myositis patients specifically target the Helicase domains of the MDA5 protein. 6th European Congress of Immunology virtual, Sep 2021, Nottingham, United Kingdom. ⟨hal-03831292⟩
- Olivier Benveniste. Inflammatory myopathies: advocating better classification and care. Seminar of the Swiss Rheumatology Academia, Jun 2021, NA, Switzerland. ⟨hal-03831924⟩
- Olivier Benveniste. Clinical diagnostic aspects in myositis. 12th European Congress of Neuropathology virtual, May 2021, Copenhague, Denmark. pp.217-241, ⟨10.5414/NPP40217⟩. ⟨hal-03831288⟩
- Céline Anquetil, Olivier Benveniste, Javid J. Moslehi, Douglas B. Johnson, Bénédicte Lebrun-Vignes, et al.. immune checkpoint inhibitor-induced myositis, the earliest and most lethal complication amongst rheumatic and musculoskeletal toxicities. 12th International congress on Autoimmunity virtual, May 2021, Athènes, Greece. ⟨hal-03834293⟩
- Olivier Benveniste. Inflammatory Autoimmune Myopathies. 16th International Congress on Neuromuscular Diseases (ICNMD202), May 2021, Valencia, Spain. ⟨hal-03831903⟩
- Olivier Benveniste. Inflammatory myopathies and lung involvement. Mayo Clinic virtual symposium on Autoimmunity and the Lung, Nov 2020, Orlando, United States. ⟨hal-03831916⟩
- Yves Allenbach. Myosites et Jak inhibiteurs. De l’immunopathologie aux biothérapies : Actualités et Controverses, Nov 2020, Paris, France. ⟨hal-03834274⟩
- Yves Allenbach. Myotoxicité. ISNI 2020 - 15E CONGRÈS DE LA SOCIÉTÉ INTERNATIONALE DE NEURO IMMUNOLOGIE, Nov 2020, Nice, France. ⟨hal-03834279⟩
- Olivier Benveniste. Inflammatory Myopathies: Issues in diagnosis and management. Virtual Agrim Neurology Update 2020, Oct 2020, NA, France. ⟨hal-03831909⟩
- Yves Allenbach. Atteinte cardiaque des myosites. Carrefour des spécialités -Médecine interne et Cardiologie, Oct 2020, Paris, France. ⟨hal-03834283⟩
- Yves Allenbach. Muscle inflammatoire. Rencontres en Immunologie et immunothérapie pratiques, Sep 2020, Paris, France. ⟨hal-03832602⟩
- Yves Allenbach. Flash Talks : quoi de neuf dans les myopathies inflammatoires ?. RENCONTRES EN IMMUNOLOGIE ET IMMUNOTHERAPIE PRATIQUES - RIIP 2020, Sep 2020, Paris, France. ⟨hal-03834273⟩
- Yves Allenbach. Myocardites : Quel bilan ? quelles étiologies?. Rencontre TUC - GIHP et GACI, Sep 2020, Paris, France. ⟨hal-03835081⟩
- Olivier Benveniste. Myositis, new treatment options. EULAR 2020 E-Congress, Jun 2020, Berlin, Germany. ⟨hal-03831898⟩
- Alexander Oldroyd, Paul New, Janine Lamb, William Ollier, Robert Cooper, et al.. Earlier cancer diagnosis after myositis onset is associated with improved long term survival: results from UK, French and Czech cohorts. 2020 Annual Conference of the British Society for Rheumatology, BSR 2020, Apr 2020, Glasgow, United Kingdom. ⟨10.1093/rheumatology/keaa110.032⟩. ⟨hal-03831704⟩
- Yves Allenbach. Rheumatic toxicities associated with immune checkpoint inhibitors: The severity of myositis. NIH-AACR CANCER, AUTOIMMUNITY, AND IMMUNOLOGY CONFERENCE, Mar 2020, Bethesda, United States. ⟨hal-03834267⟩
- Soumeya Bekri, Lénaig Abily-Donval, Wladimir Mauhin, Celine Lesueur, Olivier Benveniste, et al.. Predictive biological patterns in Fabry disease revealed by integrative omics machine learning analysis. WORLDSymposium™ 2020, Feb 2020, Orlando, United States. pp.S29, ⟨10.1016/j.ymgme.2019.11.047⟩. ⟨hal-03831698⟩
- Olivier Benveniste. Inflammatory Myopathies. The importance of being well classified!. . Departments of Neurology and Physiology and Biophysics (and the Institute of Immunology)., Jan 2020, Irvine, United States. ⟨hal-03831886⟩
- S. Toquet, B. Granger, Y. Uzunhan, G. Leroux, R. Paule, et al.. La dermatomyosite associée à l’anticorps anti-MDA5 est une maladie saisonnière : un argument pour un facteur déclenchant viral. 80ème congrès de la SNFMI, Dec 2019, Limoges, France. ⟨hal-03834042⟩
- B. Salvador, A. Cypierre, Yves Allenbach, E. Liozon, A.L. Fauchais, et al.. Amylose AL : une autre grande simulatrice. 80ème congrès de la SNFMI, Dec 2019, Limoges, France. ⟨hal-03834054⟩
- Yves Allenbach. Imagerie et explorations innovantes au cours des myopathies auto-immunes. 80ieme Congrès de la SNFMI, Dec 2019, Limoges, France. pp.A27-A29, ⟨10.1016/j.revmed.2019.10.340⟩. ⟨hal-03834254⟩
- L. Bolko, K. Didier, S. Toquet, A. Servettaz, N. Champtiaux, et al.. Signification pronostique du titre d’anticorps anti-Jo1 au cours du syndrome des anti-synthétases. 80ème congrès de la SNFMI, Dec 2019, Limoges, France. ⟨hal-03834050⟩
- S. Presente, C. Allonier, P. Rufat, N. Champtiaux, A. Rigolet, et al.. Pronostic des patients hospitalisés en médecine interne après passage aux urgences : le rôle du médecin généraliste. 80ème congrès de la SNFMI, Dec 2019, Limoges, France. ⟨hal-03834045⟩
- C. Anquetil, J.E. Salem, A. Manouchehri, O. Lambotte, B. Lebrun-Vignes, et al.. Phénotype et pronostic des atteintes systémiques induites sous inhibiteurs de check-points immunitaires. 80ème congrès de la SNFMI, Dec 2019, Limoges, France. ⟨hal-03834068⟩
- Yves Allenbach. De l’immunologie à la pratique : les auto-anticorps au coeur des myopathies auto-immunes. Journée Immunosemm, Nov 2019, Paris, France. ⟨hal-03835074⟩
- Yves Allenbach. Myopathies inflammatoires (hors myosite à inclusion) : quels traitements fondés sur des preuves ?. Deuxième journée nationale d’ophtalmologie et de médecine interne fondée sur des preuves, Nov 2019, Paris, France. ⟨hal-03834252⟩
- Yves Allenbach. Une face sombre de l’immunothérapie en cancérologie : la toxicité musculaire. 17èmes Journées de la Société Française de Myologie, Nov 2019, Marseille, France. ⟨hal-03834264⟩
- Harmen Reyngoudt, Benjamin Marty, Jean-Marc Boisserie, Julien Le Louër, Cedi Koumako, et al.. Can global muscle segmentation detect changes in neuromuscular disorders using quantitative nuclear magnetic resonance imaging?. Imaging in Neuromuscular Disease 2019: Second International Conference on Imaging in Neuromuscular Disease, Nov 2019, Berlin, Germany. pp.S1-S62, ⟨10.3233/JND-199002⟩. ⟨hal-03831354⟩
- Céline Anquetil, Olivier Benveniste, Douglas Johnson, Bénédicte Lebrun-Vignes, Joe-Elie Salem, et al.. Rheumatic toxicities associated with immune checkpoint inhibitors: An observational, retrospective, pharmacovigilance study. American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting, ACR/ARHP 2019, Nov 2019, Atlanta, United States. pp.1-5420, ⟨10.1002/art.41108⟩. ⟨hal-03831676⟩
- C. Anquetil, J. Salem, B. Lebrun-Vignes, D. Johnson, A. Mammen, et al.. Immune checkpoint inhibitor-associated myositis: a new entity with a poor prognosis. 24th International Annual Congress of the World Muscle Society (WMS), Oct 2019, Copenhague, Denmark. pp.S121, ⟨10.1016/j.nmd.2019.06.301⟩. ⟨hal-03832083⟩
- Yves Allenbach. Traitements des myopathies nécrosantes: les recommandations de l’ENMC et les perspectives. 11 eme Journée du Interdisciplinaire du Muscle Inflammatoire, Sep 2019, Paris, France. ⟨hal-03835510⟩
- Yves Allenbach. Immune Mediated Necortizing Myopathies and Antibodies. 14th Dresden Symposium on Autoantibodies, Sep 2019, Dresden, Germany. ⟨hal-03834251⟩
- Olivier Benveniste. Myositides: the importance of being well classified, from physiopathogenesis to targeted treatments. 44th Oxford Muscle Symposium, Jul 2019, Oxfard, United Kingdom. ⟨hal-03831882⟩
- Camille Houssais, Jean-Baptiste Noury, Yves Allenbach, Laure Gallay, Florence Assan, et al.. Myositis in patients with primary Sjögren's syndrome: data from a French nationwide survey. Annual European Congress of Rheumatology. EULAR 2019, Jun 2019, Madrid, Spain. pp.1171.1-1171, ⟨10.1136/annrheumdis-2019-eular.3474⟩. ⟨hal-03831358⟩
- Olivier Benveniste. Idiopathic Inflammatory Myopathies: the importance of being well classified, from physiopathogenesis to targeted treatments. 4th Neuromuscular Disorders’ Time Symposium, May 2019, Shanghai, China. ⟨hal-03831875⟩
- Yves Allenbach. Diagnosis of inflammatory myopathies. MIRCIM 2019, May 2019, Cracovie, Poland. ⟨hal-03834255⟩
- Olivier Benveniste. Inclusion Body Myositis from physiopathogenesis to treatment. Neurology Grand Rounds, Apr 2019, Kansas City, United States. ⟨hal-03831865⟩
- Olivier Benveniste. Recent advance in myositis classification and treatments. Myositis Regional Conference, Apr 2019, Kansas City, United States. ⟨hal-03831862⟩
- Olivier Benveniste. Inflammatory Myopathies: the importance of being well classified, from physiopathogenesis to targeted treatments. Allergy, Clinical Immunology & Rheumatology Divisional Conference, Apr 2019, Kansas City, United States. ⟨hal-03831870⟩
- Olivier Benveniste. Mentorship & Academic Promotion: The French System. 3rd Global Conference On Myositis, Mar 2019, Berlin, Germany. ⟨hal-03831858⟩
- Olivier Benveniste. New classification and targeted therapy in idiopathic inflammatory myopathies. Ninth France-Israel Symposium in Rheumatic Diseases, Feb 2019, Haifa, Israel. ⟨hal-03831855⟩
- Olivier Benveniste. Serology in Inflammatory Myopathies. 16th Groninger Symposium Systeemziekten, Feb 2019, Groningen, Netherlands. ⟨hal-03831852⟩
- Yves Allenbach, L. Bolko, C. Anquetil, N. Wesner, D. Amelin, et al.. Dosage de l’interféron par technologie SIMOA au cours des myopathies inflammatoires idiopathiques : un biomarqueur diagnostique et d’activité. 78e congrès de la SNFMI, Dec 2018, Grenoble, France. pp.A1, ⟨10.1016/j.revmed.2018.10.381⟩. ⟨hal-03834002⟩
- Yves Allenbach. Club Médecine interne Myosite. 78ieme Congrès de la SNFMI, Dec 2018, Grenoble, France. ⟨hal-03834104⟩
- J. Galland, M. Pha, P. Guillaume-Jugnot, N. Abisror, G. Grateau, et al.. Bienvenue au 78e congrès de la SNFMI au cœur des Alpes. 78e congrès de la SNFMI, Dec 2018, Grenoble, France. pp.A1, ⟨10.1016/j.revmed.2018.10.381⟩. ⟨hal-03833954⟩
- M. Peyre, N. Zahr, F. Cohen Aubart, Yves Allenbach, O. Benveniste, et al.. Utilité de la mesure de l’aire sous la courbe du Mycophénolate Mofétil chez les patients traités pour myopathies inflammatoires. 78e congrès de la SNFMI, Dec 2018, Grenoble, France. pp.A1, ⟨10.1016/j.revmed.2018.10.381⟩. ⟨hal-03834035⟩
- O. Landon-Cardinal, D. Bachasson, P. Guillaume-Jugnot, M. Vautier, N. Champtiaux, et al.. Évaluation de l’activité physique par accélérométrie de poignet dans le suivi des patients avec myopathies auto-immunes. 78e congrès de la SNFMI, Dec 2018, Grenoble, France. pp.A1, ⟨10.1016/j.revmed.2018.10.381⟩. ⟨hal-03833966⟩
- C. Koumakou, O. Landon-Cardinal, B. Granger, M. Vautier, H. Reyngoudt, et al.. IRM musculaire corps entier au cours des myopathies nécrosantes auto-immunes : involution graisseuse sévère axiale et pelvi-fémorale. 78e congrès de la SNFMI, Dec 2018, Grenoble, France. pp.A1, ⟨10.1016/j.revmed.2018.10.381⟩. ⟨hal-03833970⟩
- C. Anquetil, J.E. Salem, B. Lebrun-Vignes, D.B. Johnson, A.L. Mammen, et al.. Myosites induites par les Inhibiteurs de Checkpoint Immunitaires : une nouvelle myopathie auto-immune associée à une atteinte myocardique de mauvais pronostic. 78e congrès de la SNFMI, Dec 2018, Grenoble, France. pp.A1, ⟨10.1016/j.revmed.2018.10.381⟩. ⟨hal-03834040⟩
- M. Vautier, J. Schmidt, A. Berezne, N. Cordel, P. Duffau, et al.. Dermatomyosite et anticorps anti-SAE : des patients peu déficitaires avec un risque accru de troubles de la déglutition et de pneumopathie organisée. 78e congrès de la SNFMI, Dec 2018, Grenoble, France. pp.A1, ⟨10.1016/j.revmed.2018.10.381⟩. ⟨hal-03834004⟩
- O. Mangin, J.P. Bertocchio, S. Baron, G. Maruani, P. Houillier, et al.. Estimation du débit de filtration glomérulaire : des insuffisances rénales méconnues au cours de la myosite à inclusions. 78e congrès de la SNFMI, Dec 2018, Grenoble, France. pp.A1, ⟨10.1016/j.revmed.2018.10.381⟩. ⟨hal-03833994⟩
- Yves Allenbach. Classification des Myosite par les Anticorps spécifiques des myosites. 78ième Congrès de la SNFMI, Dec 2018, Grenoble, France. ⟨hal-03834105⟩
- N. Wesner, A. Uruha, N. Costedoat-Chalumeau, A. Rigolet, Y. Schoindre, et al.. Myosites associées aux anticorps anti-RNP : un phénotype homogène avec une atteinte nécrosante de bon pronostic et des manifestations systémiques persistantes. 78e congrès de la SNFMI, Dec 2018, Grenoble, France. pp.A113, ⟨10.1016/j.revmed.2018.03.363⟩. ⟨hal-03833974⟩
- Yves Allenbach. Complications auto-immunes des checkpoint inhibiteurs : le modèle des myosites et des myocardites. De l’immunopathologie aux biothérapies : Actualités et Controverses, Nov 2018, Paris, France. ⟨hal-03834249⟩
- Yves Allenbach. Nouveaux autoanticorps, nouvelles maladies. Congrès de la SFM, Nov 2018, Brest, France. ⟨hal-03834106⟩
- Yves Allenbach. Traitement par inhibiteurs de JAK des formes sévères de dermatomyosite de l’adulte et de l’enfant. 2e journée du Centre de référence des maladies rhumatologiques et auto-immunes rares de l’enfant, Nov 2018, Paris, France. ⟨hal-03834244⟩
- Yves Allenbach. Myosites : formes graves et prise en charge en réanimation. Carrefour des spécialités : médecine interne et réanimation, Nov 2018, Paris, France. ⟨hal-03834284⟩
- Loïs Bolko, Ségolène Toquet, Océane Landon-Cardinal, Karim Dorgham, Céline Anquetil, et al.. IFN level assessed by ultrasensitive detection technology in myositis patient: A promising biomarker of disease activity in dermatomyositis and anti-synthetase syndrome. American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting, ACR/ARHP 2018, Oct 2018, Chicago, United States. pp.1-3584, ⟨10.1002/art.40700⟩. ⟨hal-03831328⟩
- Céline Anquetil, Joe-Elie Salem, Benedicte Lebrun-Vignes, Douglas B Johnson, Andrew Mammen, et al.. Immune Checkpoint Inhibitor-Associated Myositis: A CharacteristicPhenotype with a Poor Outcome Related to Concomitant Myocarditis. American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting, ACR/ARHP 2018, Oct 2018, Chicago, United States. pp.1-3584, ⟨10.1002/art.40700⟩. ⟨hal-03831343⟩
- Yves Allenbach. Actualités sur les maladies autoimmunes - Actualités sur les myosites. Journée Maladie Auto-Immune - Kremlin Bicêtre, Oct 2018, Paris, France. ⟨hal-03835079⟩
- Olivier Benveniste. Inflammatory Myopathies. Kongress der Deutschen Gesellschaft für Rheumatologie, Sep 2018, Mannheim, Germany. ⟨hal-03831847⟩
- Yves Allenbach. Revue de la classification et des critères ACR/EULAR. 10 Journée Interdisciplinaire du Muscle Inflammatoire, Sep 2018, Paris, France. ⟨hal-03835514⟩
- Olivier Benveniste. Understanding necrotizing myopathy. TMA’s Annual Patient Conference, Sep 2018, Louisville, United States. ⟨hal-03831843⟩
- Yves Allenbach. Cancer and Myositis. 15th International Congress of Neuromuscular Diseases (ICNMD 2018), Jul 2018, Vienne, Austria. ⟨hal-03834102⟩
- Olivier Benveniste. Inflammatory myopathies in France, from classification to physiogenesis. 11th Japanese-French workshop on NMD, Jun 2018, Tokyo, Japan. ⟨hal-03831839⟩
- Yves Allenbach. Immune-mediated necrotizing myopathies and antibodies. 11TH INTERNATIONAL CONGRESS ON AUTOIMMUNITY, May 2018, Lisbonne, Portugal. ⟨hal-03834111⟩
- Olivier Benveniste. The classification and physiopathogenesis of the main idiopathic inflammatory myopathies.. 5th Chinese Inflammatory Myopathies Meeting,, Apr 2018, Beijing, China. ⟨hal-03831834⟩
- Olivier Benveniste. Actualités thérapeutiques des myosites. 20ème Congrès National de Médecine Interne Tunisien, Mar 2018, Hammamet, Tunisie. ⟨hal-03831827⟩
- Olivier Benveniste. Les nouvelles myopathies inflammatoires : apport de l’immunologie dans leur classification.. 20ème Congrès National de Médecine Interne Tunisien, Mar 2018, Hammamet, Tunisie. ⟨hal-03831830⟩
- Yves Allenbach. Dermatomyositis and IFN. Euromyositis registry and MYONET meeting, Feb 2018, Prague, Czech Republic. ⟨hal-03834100⟩
- Yves Allenbach. Nouvelle classification des myopathies inflammatoires : place des anticorps spécifiques. Académie nationale de médecine, Jan 2018, Paris, France. ⟨hal-03834242⟩
- W. Mauhin, L. Arouche-Delaperche, D. Amelin, J. Dimitrov, Yves Allenbach, et al.. Les anticorps anti-HMGCoA-reductase associés aux myopathies nécrosantes auto-immunes ont une forte affinité pour l’HMGCoA-reductase sans pour autant l’inhiber. 76eme Congrès de la SNFMI Franco-Maghrébin, Dec 2017, Paris, France. ⟨hal-03833921⟩
- G. Monseau, O. Landon-Cardinal, W. Stenzel, Y. Schoindre, K. Mariampillai, et al.. Dermatomyosites (DM) à anticorps anti-Mi2 revisitées : DM pure avec nécrose musculaire et haut risque de malignité associée. 76eme Congrès de la SNFMI Franco-Maghrébin, Dec 2017, Paris, France. ⟨hal-03833897⟩
- O. Landon-Cardinal, Yves Allenbach, A. Soulages, A. Rigolet, B. Hervier, et al.. Rituximab dans le traitement des MNAI anti-HMGCR : efficacité modeste et IgIV-dépendance. 76eme Congrès de la SNFMI Franco-Maghrébin, Dec 2017, Paris, France. ⟨hal-03833941⟩
- O. Benveniste, J.Y. Hogrel, M. Annoussamy, A. Rigolet, B. Hervier, et al.. Premiers résultats prometteurs de l’essai rapamycine versus placebo pour le traitement de la myosite à inclusions (RAPAMI). 76eme Congrès de la SNFMI Franco-Maghrébin, Dec 2017, Paris, France. ⟨hal-03833928⟩
- G. Dzangué-Tchoupou, Yves Allenbach, C. Aurélien, D. Amelin, W. Mauhin, et al.. Cytométrie de masse : caractéristiques phénotypiques de la réponse immunitaire systémique au cours des myosites. 76eme Congrès de la SNFMI Franco-Maghrébin, Dec 2017, Paris, France. ⟨hal-03833932⟩
- K. Mariampillai, B. Granger, M. Guiguet, D. Amelin, E. Hachulla, et al.. Une nouvelle classification des myopathies inflammatoires idiopathiques basée sur des manifestations cliniques et les anticorps spécifiques des myosites. 76ÈME CONGRÈS DE LA SNFMI - FRANCO-MAGHRÉBIN, Dec 2017, Paris, France. ⟨hal-03833849⟩
- O. Benveniste, D. Bachasson, O. Landon-Cardinal, N. Champtiaux, L. Gilardin, et al.. Une solution nouvelle pour l’évaluation des myosites : la mesure de l’activité physique quotidienne par accéléromètrie. 76eme Congrès de la SNFMI Franco-Maghrébin, Dec 2017, Paris, France. ⟨hal-03833904⟩
- L. Gallay, N. Streichenberger, O. Benveniste, Yves Allenbach. Myosite focale : une maladie méconnue. 76eme Congrès de la SNFMI Franco-Maghrébin, Dec 2017, Paris, France. ⟨hal-03833916⟩
- A. Uruha, Yves Allenbach, T. Maisonobe, S. Léonard-Louis, J.L. Charuel, et al.. Myxovirus resistance A : un marqueur histologique diagnostique pour la dermatomyosite. 76eme Congrès de la SNFMI Franco-Maghrébin, Dec 2017, Paris, France. ⟨hal-03833925⟩
- S. Toquet, O. Landon-Cardinal, P. Guillaume-Jugnot, N. Champtiaux, L. Ladislau, et al.. Les inhibiteurs de la voie des Janus-kinases : un traitement prometteur de la dermatomyosite pour inhiber de la voie de l’interféron,. 76eme Congrès de la SNFMI Franco-Maghrébin, Dec 2017, Paris, France. ⟨hal-03833946⟩
- Yves Allenbach, A. Rigolet, S. Louis-Leonard, E. Salort-Campana, L. Gilardin, et al.. Myopathie axiale vacuolaire avec rigidité : une nouvelle entité reliée aux gammapathies monoclonales. 76eme Congrès de la SNFMI Franco-Maghrébin, Dec 2017, Paris, France. ⟨hal-03833911⟩
- Olivier Benveniste, Jean-Yves Hogrel, Melanie Annoussamy, Damien Bachasson, Aude Rigolet, et al.. Rapamycin vs. Placebo for the Treatment of Inclusion Body Myositis: improvement of the 6 min walking distance, a functional scale, the FVC and muscle quantitative MRI. 2017 ACR/ARHP Annual Meeting, Nov 2017, San Diego, United States. pp.1-3584. ⟨hal-03831822⟩
- O. Landon-Cardinal, G. Monseau, Y. Schoindre, A. Rigolet, N. Champtiaux, et al.. Anti-Mi2 dermatomyositis revisited: pure DM phenotype with muscle fiber necrosis and high risk of malignancy. 22nd International Congress of the World Muscle Society, Oct 2017, Saint Malo, France. pp.S153, ⟨10.1016/j.nmd.2017.06.218⟩. ⟨hal-01664160⟩
- Yves Allenbach. Myopathie et gammapathie Monoclonae. 9 eme Journée Interdisciplinaire du Muscle inflammatoire, Sep 2017, Paris, France. ⟨hal-03835519⟩
- Olivier Benveniste. Promising Research in Inclusion Body Myositis. TMA’s Annual Patient Conference, Sep 2017, San Diego, United States. ⟨hal-03831792⟩
- Olivier Benveniste. Myositis-specific antibodies and what they tell us about the different forms of myositis.. 2nd Global Conference on Myositis, May 2017, Potomac, United States. ⟨hal-03831781⟩
- Olivier Benveniste. Prognosis in adult myositis. 2nd Global Conference on Myositis, May 2017, Potomac, United States. ⟨hal-03831785⟩
- Olivier Benveniste. Classification and treatments of myositis. Third Lebanon congress of Internal Medicine, Jan 2017, Beyrouth, Lebanon. ⟨hal-03831774⟩
Poster de conférence
- Mridul Johari, Daphne Wijnbergen, Alaa Khan, Pedro Machado, Henry Houlden, et al.. Elucidating the molecular biology of Inclusion body Myositis through multi-omics analysis. Solve-RD, Solving the unsolved Rare Diseases, Final Meeting 2023, Apr 2023, Prague, Czech Republic. ⟨hal-04086230⟩
- Corinna Preusse, Andreas Hentschel, Albert Sickmann, Yves Allenbach, Olivier Benveniste, et al.. Upregulation of structural proteins in immune-mediated necrotizing myopathy is independent of underlying autoantibodies. 4TH GLOBAL CONFERENCE ON MYOSITIS 2022, Jun 2022, Prague, Czech Republic. ⟨hal-03832549⟩
- Loïs Bolko, Sarah Leonard-Louis, Lukshe Kanagaratnam, Charlotte Pineau, Jean-Hugues Salmon, et al.. Diagnostic accuracy of electromyogram for myositis. 4th Global Conference On Myositis (GCOM 2022), Jun 2022, Prague, Czech Republic. ⟨hal-03832588⟩
- Yves Allenbach, Guillaume Mercy, Jean-Francois Deux, Frantz Foissac, Yoland Shoindre, et al.. Diagnosis accuracy of muscule MRI for autoimmune myopathies: Multicentric prospective study (DARWIM). 4th Global Conference On Myositis (GCOM 2022), Jun 2022, Prague, Czech Republic. ⟨hal-03832571⟩
- Céline Anquetil, Nozomu Tawara, Maxime Lecerf, Damien Amelin, Alexandrine Mahoudeau, et al.. Antigenic targets in anti-SRP immune-mediated necrotizing myopathy. 4th Global Conference On Myositis (GCOM 2022), Jun 2022, Prague, Czech Republic. ⟨hal-03832564⟩
- Julian Dal Cin, Céline Anquetil, Mehdi Touat, Lisa Salhi, Hossein Khademian, et al.. Description of macrophages in idiopathic inflammatory myopathies using in-situ RNAseq. 4th Global Conference On Myositis (GCOM 2022), Jun 2022, Prague, Czech Republic. ⟨hal-03832557⟩
- Alexandrine Mahoudeau, Céline Anquetil, Nozomu Tawara, Hossein Khademian, Damien Amelin, et al.. Myostatin in idiopathic inflammatory myopathies: serum assessment and disease activity. 4th Global Conference On Myositis (GCOM 2022), Jun 2022, Prague, Czech Republic. ⟨hal-03832567⟩
- Samy Mensi, Horstense Chassepot, Dris Kharroubi, Lotta Plomp, Baptiste Abbar, et al.. 18-FDG PET-CT diagnostic value in immune checkpoint inhibitor-induced myositis. 4th Global Conference On Myositis (GCOM 2022), Jun 2022, Prague, Czech Republic. ⟨hal-03832576⟩
- M. Lekieffre, Yves Allenbach, A. Meyer, S. Louis-Léonard, O. Benveniste, et al.. Refining rheumatoid arthritis and myositis overlap: a multicentric French case-series. 4th Global Conference On Myositis (GCOM 2022), Jun 2022, Prague, Czech Republic. ⟨hal-03832585⟩
- Eveline Van Gompel, Catia Cerqueira, Karine Chemin, Begum Horuluoglu, Angeles Shunashy Galindo- Feria, et al.. MDA5 helicase domains identified as the main targets of anti-MDA5 autoantibodies in european dermatomyositis patients. American College of Rheumatology Convergence, ACR 2021, Nov 2021, San Diego, United States. 73 (S9), pp.1-4259, 2021, ⟨10.1002/art.41966⟩. ⟨hal-03831280⟩
- Loïs Bolko, Sarah Léonard-Louis, Jean Hugues Salmon, Olivier Benveniste, Yves Allenbach, et al.. Diagnostic accuracy of electromyogram for myositis. American College of Rheumatology Convergence, ACR 2021, Nov 2021, San Diego, United States. 73 (S9), pp.1-4259, 2021, ⟨10.1002/art.41966⟩. ⟨hal-03831303⟩
- Alexandrine Mahoudeau, Céline Anquetil, Nozomu Tawara, Hossein Khademian, Damien Amelin, et al.. Myostatin in idiopathic inflammatory myopathies: Seric assessment and disease activity. American College of Rheumatology Convergence, ACR 2021, Nov 2021, San Diego, United States. 73 (S9), pp.1-4259, 2021, ⟨10.1002/art.41966⟩. ⟨hal-03831267⟩
- Chassepot Hortense, Plomp Lotta, Psimaras Dimitri, Maisonobe Thierry, Plu Isabelle, et al.. Immune checkpoint inhibitor-related myotoxicity : Musculoskeletal and/or neuromuscular junction disorder ?. American College of Rheumatology Convergence, ACR 2021, Nov 2021, San Diego, United States. 73 (S9), pp.1-4259, 2021, ⟨10.1002/art.41966⟩. ⟨hal-03831277⟩
- Corinna Preuße, Pascale Eede, Lucie Heinzeling, Kiara Freitag, Randi Koll, et al.. NanoString technology distinguishes anti-TIF-1γ+ from anti-Mi-2+ dermatomyositis patients. 12th European Congress of Neuropathology virtual, May 2021, NA, Sweden. 40 (07), pp.149, 2021, ⟨10.5414/NPP40M01⟩. ⟨hal-03831768⟩
- Thierry Poynard, Olivier Deckmyn, Marika Rudler, Valentina Peta, Yen Ngo, et al.. Performance of serum apolipoprotein-a1 as a sentinel of COVID-19. 71st Annual Meeting of the American Association for the Study of Liver Diseases, AASLD, Nov 2020, Boston, United States. 72 (S1), 2020, ⟨10.1002/hep.31579⟩. ⟨hal-03831756⟩
- Alexandre Le Joncour, Corinne Frère, Isabelle Martin-Toutain, Paul Gougis, Pascale Ghillani-Dalbin, et al.. Antiphospholipid Antibodies and Thrombotic Events in COVID-19 Patients Hospitalized in Medicine Ward. ACR Convergence 2020, Nov 2020, Online, United States. , 20 (2), pp.102729, 2021, Elsevier Public Health Emergency Collection. ⟨10.1016/j.autrev.2020.102729⟩. ⟨hal-03831591⟩
- Chloé Comarmond, Mathilde Leclercq, Gaëlle Leroux, Cindy Marques, Alexandre Le Joncour, et al.. 2019 Novel Coronavirus Disease (COVID-19) in Patients with Large-Vessels Vasculitis: Single-centre Experience in Paris. American College of Rheumatology Convergence, ACR 2020, Nov 2020, NA, United States. 72 (S10), pp.1-4259, 2020, ⟨10.1002/art.41538⟩. ⟨hal-03831597⟩
- Alexander Oldroyd, Paul New, Janine Lamb, William Ollier, Robert Cooper, et al.. Earlier Cancer Diagnosis after Idiopathic Inflammatory Myopathy Onset Is Associated with Improved Long Term Survival - Results from Four European Cohorts. American College of Rheumatology Convergence, ACR 2020 virtual, Nov 2020, NA, United States. ⟨hal-03831570⟩
- Loïs Bolko, Kevin Didier, Jean-Hugues Salmon, Makoto Miyara, Segolene Toquet, et al.. Anti-Jo1 Antibody Quantification Serve as a Prognostic Factor in Antisynthetase Syndrom. American College of Rheumatology Convergence, ACR 2020 virtual, Nov 2020, NA, United States. 72 (S10), pp.1-4259, 2020, ⟨10.1002/art.41538⟩. ⟨hal-03831580⟩
- Océane Landon-Cardinal, Kuberaka Mariampillai, Céline Anquetil, Aude Rigolet, Baptiste Hervier, et al.. Chronic disease course and ivig-dependance in long-term follow-up of anti-hmgcr immune-mediated necrotizing myopathy. American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting, ACR/ARHP 2019, Nov 2019, Atlanta, United States. 71 (S10), pp.1-5420, 2019, ⟨10.1002/art.41108⟩. ⟨hal-03831692⟩
- Océane Landon-Cardinal, Perrine Guillaume-Jugnot, Lois Bolko, Ségolène Toquet, Aude Rigolet, et al.. JAK Inhibitors: A Promising Molecular- targeted Therapy in Dermatomyositis. American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting, ACR/ARHP 2019, Nov 2019, Atlanta, United States. 71 (S10), pp.1-5420, 2019, ⟨10.1002/art.41108⟩. ⟨hal-03831682⟩
- Camille Houssais, J Noury, Y. Allenbach, L Gallay, F Assan, et al.. Myositis in patients with primary Sjögren’s syndrome: data from a French nationwide survey.. EULAR, Jun 2019, Madrid, Spain. ⟨hal-02152824⟩
- Céline Anquetil, Joe-Elie Salem, Bénédicte Lebrun-Vignes, Douglas Johnson, Andrew Mammen, et al.. Immune checkpoint inhibitor-associated myositis: a new entity amongst immune inflammatory myopathies with a poor prognosis. IFODS 2019, Jun 2019, Paris, France. ⟨hal-03834301⟩
- Barbara Paesler, Laure Gallay, Yves Allenbach, Olivier Benveniste, Nathalie Streichenberger, et al.. Anti-Jo-1 antibody-positive patients show different clinical symptoms, histological features and molecular gene expression compared to anti-PL-7 and anti-PL-12 antibody-positive patients. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832074⟩
- Olivier Mangin, Jean Philippe Bertocchio, Yves Allenbach, Gerard Maruani, Pascal Houillier, et al.. Creatinine- and cystatin C-estimated glomerular filtration rate for estimating renal function during inclusion body myositis. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832035⟩
- Alexandrine Mahoudeau, Leandro Ladislau, Yves Allenbach, Thérèse Croughs, Allia Gati, et al.. Evaluation of the effect of neutralizing anti-IFN-α antibodies produced in one SLE patient vaccinated with IFN-K on myotubes atrophy induced by type I interferon. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832054⟩
- Camille Rasmussen, Laure Gallay, Alain Meyer, Delphine Larivière, Sarah Leonard-Louis, et al.. Anti-NXP2 Dermatomyositis: a severe muscle and skin disease. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832033⟩
- Samuel Knauss, Corinna Preuße, Yves Allenbach, Sarah Leonard-Louis, Mehdi Touat, et al.. The role of dysfunctional T-cells in immune mediated myositis. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832038⟩
- Yves Allenbach, Emmanuelle Salort-Campana, Edoardo Malfatti, Bruno Eymard, Shahram Attarian, et al.. Vacuolar myopathy with monoclonal gammapathy and stiffness: A new Monoclonal gammopathy of muscle significance. GCOM 2019 - Global Conference on Myositis 2019, Mar 2019, Berlin, Germany. , BMC Rheumatology Poster presentation n° P133, 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832060⟩
- Marion Peyre, Nicolas Champtiaux, Kuberaka Mariampillai, Océane Landon-Cardinal, Mathieu Vautier, et al.. Clinical presentation and outcome in anti-SRP IMNM: french cohort of 54 patients. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832041⟩
- Nadège Wesner, Akinori Uruha, Shigeaki Suzuki, Kuberaka Mariampillai, Benjamin Granger, et al.. Anti-RNP antibodies delineate a subgroup of necrotizing myositis. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832045⟩
- Kubéraka Mariampillai, Ségolène Toquet, Yurdagul Uzunhan, Gaelle Leroux, Laure Gallay, et al.. Dermatomyositis with anti-MDA5 auto-antibodies: is there a seasonal pattern of disease onset?. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832031⟩
- Océane Landon-Cardinal, Kuberaka Mariampillai, Céline Anquetil, Aude Rigolet, Baptiste Hervier, et al.. Chronic disease course and IVIg-dependance in long-term follow-up of anti-HMGCR immune-mediated necrotizing myopathy. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832037⟩
- Mathieu Vautier, Pierre Duffau, Olivier Chosidow, Alice Berezne, Nadege Cordel, et al.. Dermatomyositis associated with antibodies to small ubiquitin like modifier activating enzyme: a retrospective series of 41 cases. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832029⟩
- Gaelle Dzangué-Tchoupou, Yves Allenbach, Corinna Preusse, Werner Stenzel, Olivier Benveniste. Mass cytometry reveals an impairment of B cell homeostasis in Anti-synthetase syndrome. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832069⟩
- Audrey Aussy, Manuel Fréret, Laure Gallay, Laurent Drouot, Fabienne Jouen, et al.. The IgG2 isotype of anti-transcription intermediary factor 1-gamma autoantibodies is a biomarker of mortality and cancer in adult dermatomyositis. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832023⟩
- Audrey Aussy, Maire Chilles, Laurent Drouot, Fabienne Jouen, Christophe Arnoult, et al.. murin model of anti-TIF1gamma dermatomyositis: preliminary results. Global Conference on Myositis 2019 (GCOM 2019), Mar 2019, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832032⟩
- Maximilien Sochala, Raphaël Porcher, Tanya Stojkovic, Henri Marc Bécane, Anthony Béhin, et al.. High Risk of Fatal and Non-Fatal Venous Thromboembolism in Myotonic Dystrophy. 6th International Congress of Myology, Mar 2019, Bordeaux, France. ⟨hal-04020135⟩
- Yves Allenbach, Yurdagul Uzunhan, Ségolène Toquet, Gaëlle Leroux, Laure Gallay, et al.. Moving from Dermatomyositis Associated with Anti-MelanomaDifferentiation-Associated Gene 5 Antibody to Anti-MelanomaDifferentiation-Associated Gene 5 Syndrome. American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting, ACR/ARHP 2018, Oct 2018, Chicago, United States. 70, pp.1-3584, 2018, ⟨10.1002/art.40700⟩. ⟨hal-03831335⟩
- Yves Allenbach, Yurdagul Uzunhan, Ségolène Toquet, Gaëlle Leroux, Laure Gallay, et al.. Moving from Dermatomyositis Associated with Anti-Melanoma Differentiation-Associated Gene 5 Antibody to Anti-Melanoma Differentiation-Associated Gene 5 Syndrome. the 2018 ACR/ARP Annual Meeting, Oct 2018, Chicago, United States. , Arthritis Rheumatol., 70 (suppl 10), pp.Abstract Number: 1331. ⟨hal-02005435⟩
- Yannick Dieudonné, Yves Allenbach, Olivier Benveniste, Sarah Léonard-Louis, Baptiste Hervier, et al.. Granulomatous Myositis: Heterogeneity and Response to Treatment. American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting, ACR/ARHP 2018, Oct 2018, Chicago, United States. 70, pp.1-3584, 2018, ⟨10.1002/art.40700⟩. ⟨hal-03831339⟩
- Océane Landon-Cardinal, Damien Bachasson, Perrine Guillaume, Mathieu Vautier, Nicolas Champtiaux, et al.. Physical Activity Monitoring Using Wrist-Worn Accelerometer in theAssessment and Follow-up of Patients with Myositis. American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting, ACR/ARHP 2018, Oct 2018, Chicago, United States. 70, pp.1-3584, 2018, ⟨10.1002/art.40700⟩. ⟨hal-03831348⟩
- Céline Anquetil, Joe-Elie Salem, Bénédicte Lebrun-Vignes, Douglas B. Johnson, Andrew L. Mammen, et al.. Immune checkpoint inhibitor-associated myositis: a new and severe entity amongst immune inflammatory myopathies. Global Conference on Myositis 2019 (GCOM 2019), Mar 2017, Berlin, Germany. 3 (S1), pp.31, 2019, ⟨10.1186/s41927-019-0078-3⟩. ⟨hal-03832066⟩
Pré-publications, Documents de travail
- Bolko Loïs, Celine Anquetil, Alba Llibre, Solene Maillard, Damien Amelin, et al.. Ultrasensitive Interferons quantification in idiopathic inflammatory myopathies serve as biomarkers of activity in dermatomyositis and anti-synthetase syndrome. 2021. ⟨pasteur-03252308⟩
Thèses
- Wladimir Mauhin. Exploration des mécanismes inflammatoires impliqués dans la physiopathologie de la maladie de Fabry et la réponse à l’enzymothérapie substitutive. Médecine humaine et pathologie. Sorbonne Université, 2018. Français. ⟨NNT : 2018SORUS610⟩. ⟨tel-03153269⟩
- Gaëlle Dzangué Tchoupou. Caractérisation des réponses immunitaires chez les patients atteints de myopathies auto-immunes idiopathiques. Immunologie. Sorbonne Université, 2018. Français. ⟨NNT : 2018SORUS171⟩. ⟨tel-02457144⟩
- Yves Allenbach. Rôle des lymphocytes T régulateurs dans un modèle murin de myopathie inflammatoire et implications dans la physiopathologie et la thérapie de la Myosite à Inclusions. Immunologie. Université Pierre et Marie Curie - Paris VI, 2011. Français. ⟨NNT : 2011PA066615⟩. ⟨tel-00824661⟩