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Equipe LE PANSE

Myasthenia Gravis: étiologie, physiopathologie & approches thérapeutiques

La myasthénie fait partie des maladies auto-immunes qui touchent plus de 5% de la population. Il s’agit de maladies multifactorielles qui mettent en jeu un terrain génétique et hormonal prédisposant, des anomalies du système immunitaire, et qui sont déclenchées par des facteurs encore non-identifiés. La myasthénie est due à des auto-anticorps dirigés contre des composants de la jonction neuromusculaire, principalement le récepteur de l’acétylcholine (RACh, 85% des cas) mais parfois aussi le récepteur tyrosine-kinase spécifique du muscle (MuSK) ou la protéine LRP4 interagissant avec l’agrine. Ces auto-anticorps diminuent l’efficacité de la transmission neuromusculaire et entrainent une fatigabilité anormale des muscles.

Le thymus est très probablement le site d’initiation de la myasthénie avec anticorps anti-RACh. En effet des anomalies histologiques du thymus sont très fréquentes : 50-60% des patients présentent une hyperplasie folliculaire avec centres germinatifs et 10-15% une tumeur du thymus. La thymectomie est l’un des traitements proposés à ces patients.

Les travaux de recherche développés par l’équipe ont pour objectifs de comprendre les mécanismes étiologiques et physiopathologiques impliqués dans la myasthénie, et de proposer de nouvelles thérapies. Plus spécifiquement, nos objectifs sont de :

  • Elucider les mécanismes étiologiques impliqués dans l’auto-immunité en analysant l’impact des hormones sexuelles et des perturbateurs endocriniens dans les processus de tolérance centrale.
  • Comprendre les mécanismes cellulaires et moléculaires à l’origine de l’inflammation et du remodelage thymique observé chez les patients.
  • Étudier les défauts immuno-régulateurs dans la myasthénie en étudiant le phénotype fonctionnel des cellules périphériques et thymiques par la cytométrie de masse (CyTOF).
  • Développer de nouvelles approches thérapeutiques. Dans ce contexte, nous étudions le potentiel immuno-modulateur et thérapeutique des cellules souches mésenchymateuses, et le potentiel de molécules interférant avec les voies inflammatoires.
  • Rechercher des biomarqueurs dans le sérum des patients pour suivre l’évolution de la maladie et la réponse aux divers traitements.

AFMTLT Equipe 7 Rozen Le Panse 2024 JYS
AFMTLT Le Panse 2024 JYS

Contacts :

Rozen Le Panse

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219 documents

Articles dans une revue153 document

  • Anaís Mariscal, Carmen Martínez, Lea Goethals, Elena Cortés-Vicente, Elisabeth Moltó, et al.. Modified radioimmunoassay versus ELISA to quantify anti-acetylcholine receptor antibodies in a mouse model of myasthenia gravis. Journal of Immunological Methods, 2024, 534, pp.113748. ⟨10.1016/j.jim.2024.113748⟩. ⟨hal-04774927⟩
  • Henry Kaminski, Linda Kusner, Gary Cutter, Rozen Le Panse, Cameron Wright, et al.. Does Surgical Removal of the Thymus Have Deleterious Consequences?. Neurology, 2024, 102 (12), pp.e209482. ⟨10.1212/WNL.0000000000209482⟩. ⟨hal-04617840⟩
  • Frédérique Truffault, Ludivine Auger, Nadine Dragin, Jean-Thomas Vilquin, Elie Fadel, et al.. Comparison of juvenile and adult myasthenia gravis in a French cohort with focus on thymic histology. Scientific Reports, 2024, 14 (1), pp.13955. ⟨10.1038/s41598-024-63162-0⟩. ⟨hal-04617835⟩
  • Frédérique Truffault, Ludivine Auger, Nadine Dragin, Jean-Thomas Vilquin, Elie Fadel, et al.. Comparison of juvenile and adult myasthenia gravis in a French cohort with focus on thymic histology. Scientific Reports, 2024, 14 (1), pp.13955. ⟨10.1038/s41598-024-63162-0⟩. ⟨hal-04796299⟩
  • Cyprien Denoeud, Guotian Luo, Joseph Paquet, Julie Boisselier, Pauline Wosinski, et al.. Enzyme-controlled, nutritive hydrogel for mesenchymal stromal cell survival and paracrine functions. Communications Biology, 2023, 6 (1), pp.1266. ⟨10.1038/s42003-023-05643-y⟩. ⟨hal-04442110⟩
  • Cyprien Denoeud, Guotian Luo, Joseph Paquet, Julie Boisselier, Pauline Wosinski, et al.. Enzyme-controlled, nutritive hydrogel for mesenchymal stromal cell survival and paracrine functions. Communications Biology, 2023, 6 (1), pp.1266. ⟨10.1038/s42003-023-05643-y⟩. ⟨hal-04796319⟩
  • José A Villegas, Jérôme van Wassenhove, Judith Merrheim, Karen Matta, Samy Hamadache, et al.. Blocking interleukin-23 ameliorates neuromuscular and thymic defects in myasthenia gravis. Journal of Neuroinflammation, 2023, 20 (1), pp.9. ⟨10.1186/s12974-023-02691-3⟩. ⟨hal-03972909⟩
  • Cloé Payet, Axel You, Odessa-Maud Fayet, Edouard Hemery, Frederique Truffault, et al.. Central role of macrophages and nucleic acid release in Myasthenia Gravis thymus. Annals of Neurology, 2023, 93 (4), pp.643-654. ⟨10.1002/ana.26590⟩. ⟨pasteur-03927224⟩
  • Lidia Almenara-Fuentes, Silvia Rodriguez-Fernandez, Estela Rosell-Mases, Katerina Kachler, Axel You, et al.. A new platform for autoimmune diseases. Inducing tolerance with liposomes encapsulating autoantigens. Nanomedicine: Nanotechnology, Biology and Medicine, 2023, pp.102635. ⟨10.1016/j.nano.2022.102635⟩. ⟨hal-03885962⟩
  • Julien Verdier, Odessa-Maud Fayet, Edouard Hemery, Frédérique Truffault, Natalia Pinzón, et al.. Single-cell mass cytometry on peripheral cells in Myasthenia Gravis identifies dysregulation of innate immune cells. Frontiers in Immunology, 2023, 14, ⟨10.3389/fimmu.2023.1083218⟩. ⟨hal-03972888⟩
  • Tanya Stojkovic, Marion Masingue, Helène Turmel, Marianne Hezode-Arzel, Anthony Béhin, et al.. Diagnostic yield of a practical electrodiagnostic protocol discriminating between different congenital myasthenic syndromes. Neuromuscular Disorders, 2022, 32 (11-12), pp.870-878. ⟨10.1016/j.nmd.2022.10.001⟩. ⟨hal-04074000⟩
  • Cloé Payet, Axel You, Odessa-Maud Fayet, Nadine Dragin, Sonia Berrih-Aknin, et al.. Myasthenia Gravis: An Acquired Interferonopathy?. Cells, 2022, 11 (7), pp.1218. ⟨10.3390/cells11071218⟩. ⟨hal-03641038⟩
  • Laura Le Gall, William J Duddy, Cecile Martinat, Virginie Mariot, Owen Connolly, et al.. Muscle cells of sporadic amyotrophic lateral sclerosis patients secrete neurotoxic vesicles. Journal of Cachexia, Sarcopenia and Muscle, 2022, 13 (2), pp.1385 - 1402. ⟨10.1002/jcsm.12945⟩. ⟨hal-04767184⟩
  • Maartje Huijbers, Alexander Marx, Jaap Plomp, Rozen Le Panse, William Phillips. Advances in the understanding of disease mechanisms of autoimmune neuromuscular junction disorders. The Lancet Neurology, 2022, 21 (2), pp.163-175. ⟨10.1016/S1474-4422(21)00357-4⟩. ⟨hal-03563023⟩
  • Konstantinos Savvatis, Christoffer Rasmus Vissing, Lori Klouvi, Anca Rezeda Florian, Mehjabin Rahman, et al.. Cardiac Outcomes in Adults With Mitochondrial Diseases. Journal of the American College of Cardiology, 2022, 80 (15), pp.1421-1430. ⟨10.1016/j.jacc.2022.08.716⟩. ⟨hal-03837169⟩
  • Scott Thomas, Odessa-Maud Fayet, Frédérique Truffault, Elie Fadel, Bastien Provost, et al.. Altered expression of fragile X mental retardation-1 (FMR1) in the thymus in autoimmune myasthenia gravis. Journal of Neuroinflammation, 2021, 18 (1), ⟨10.1186/s12974-021-02311-y⟩. ⟨hal-03441468⟩
  • Alexandra Bayer Wildberger, Judith Lorant, Jean-Thomas Vilquin. Les exosomes, des messagers intercellulaires naturels aux mécanismes polyvalents pour le traitement des myopathies?. Les Cahiers de Myologie, 2021, 37 (1), pp.44-45. ⟨hal-03440216⟩
  • Lucie Isoline Pisella, Sara Fernandes, Guilhem Sole, Tanya Stojkovic, Celine Tard, et al.. A multicenter cross-sectional French study of the impact of COVID-19 on neuromuscular diseases. Orphanet Journal of Rare Diseases, 2021, 16 (1), pp.450. ⟨10.1186/s13023-021-02090-y⟩. ⟨hal-03470914⟩
  • S Birnbaum, R Porcher, P Portero, B Clair, S Demeret, et al.. Home-based exercise in autoimmune myasthenia gravis: A randomized controlled trial. Neuromuscular Disorders, 2021, 31 (8), pp.726-735. ⟨10.1016/j.nmd.2021.05.002⟩. ⟨hal-03442076⟩
  • Sonia Berrih-Aknin, Kristl G Claeys, Nancy Law, Renato Mantegazza, Hiroyuki Murai, et al.. Patient-reportedimpact of myasthenia gravis in the real world: protocol for a digital observational study (MyRealWorld MG). BMJ Open, 2021, 11 (7), pp.e048198. ⟨10.1136/bmjopen-2020-048198⟩. ⟨hal-03296042⟩
  • Jean-Thomas Vilquin, Alexandra Bayer, Rozen Le Panse, Sonia Berrih-Aknin. The muscle is not a passive target in Myasthenia Gravis. Frontiers in Neurology, 2020, 10, pp.1343. ⟨hal-02396099⟩
  • Inès Barthélémy, Jean-Laurent Thibaud, Pauline de Fornel, Marco Cassano, Isabel Punzon, et al.. In vivo stem cell tracking using scintigraphy in a canine model of DMD. Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-66388-w⟩. ⟨hal-02888783⟩
  • Jessy Etienne, Pierre Joanne, Cyril Catelain, Stéphanie Riveron, Alexandra Bayer Wildberger, et al.. The authors reply: Comment on: “Aldehyde dehydrogenases contribute to skeletal muscle homeostasis in healthy, aging, and Duchenne muscular dystrophy patients” by Etienne et al.. Journal of Cachexia, Sarcopenia and Muscle, 2020, ⟨10.1002/jcsm.12629⟩. ⟨hal-03038617⟩
  • Anna Rostedt Punga, Linda Kusner, Sonia Berrih-Aknin, Rozen Le Panse. Editorial: Advances in Autoimmune Myasthenia Gravis. Frontiers in Immunology, 2020, ⟨10.3389/fimmu.2020.01688⟩. ⟨hal-03052107⟩
  • Jessy Etienne, Pierre Joanne, Cyril Catelain, Stéphanie Riveron, Alexandra Clarissa Bayer, et al.. Aldehyde dehydrogenases contribute to skeletal muscle homeostasis in healthy, aging, and Duchenne muscular dystrophy patients. Journal of Cachexia, Sarcopenia and Muscle, 2020, 11 (4), pp.1047-1069. ⟨10.1002/jcsm.12557⟩. ⟨hal-03082621⟩
  • Isabel Punzón, David Mauduit, Bryan Holvoet, Jean-Laurent Thibaud, Pauline de Fornel, et al.. In Vivo Myoblasts Tracking Using the Sodium Iodide Symporter Gene Expression in Dogs. Molecular Therapy - Methods and Clinical Development, 2020, 17, pp.317-327. ⟨10.1016/j.omtm.2019.12.011⟩. ⟨hal-03082528⟩
  • Judith Merrheim, José Villegas, Jérôme van Wassenhove, Rémi Khansa, Sonia Berrih-Aknin, et al.. Estrogen, estrogen-like molecules and autoimmune diseases. Autoimmunity Reviews, 2020, 19 (3), pp.102468. ⟨10.1016/j.autrev.2020.102468⟩. ⟨hal-03824055⟩
  • Mélanie A Cron, Emilie Guillochon, Linda Kusner, Rozen Le Panse. Role of miRNAs in Normal and Myasthenia Gravis Thymus. Frontiers in Immunology, 2020, 1, pp.1074. ⟨10.3389/fimmu.2020.01074⟩. ⟨hal-02897998⟩
  • Frédérique Truffault, Dani Nazzal, Julien Verdier, Angeline Gradolatto, Elie Fadel, et al.. Comparative Analysis of Thymic and Blood Treg in Myasthenia Gravis: Thymic Epithelial Cells Contribute to Thymic Immunoregulatory Defects. Frontiers in Immunology, 2020, 11, pp.782. ⟨10.3389/fimmu.2020.00782⟩. ⟨hal-02970791⟩
  • Mélanie A Cron, Cloé A Payet, Odessa-Maud Fayet, Solène Maillard, Frédérique Truffault, et al.. Decreased expression of miR-29 family associated with autoimmune myasthenia gravis. Journal of Neuroinflammation, 2020, 17 (1), pp.294. ⟨10.1186/s12974-020-01958-3⟩. ⟨hal-02978703⟩
  • Claire Mj Lefeuvre, Cloé Payet, Odessa-Maud Fayet, Solène Maillard, Frédérique Truffault, et al.. Risk factors associated with myasthenia gravis in thymoma patients: The potential role of thymic germinal centers. Journal of Autoimmunity, 2020, 106, pp.102337. ⟨10.1016/j.jaut.2019.102337⟩. ⟨pasteur-02315094⟩
  • Alexandra Clarissa Bayer Wildberger, Jean-Thomas Vilquin. Évidence préclinique de l’effet thérapeutique de l’efgartigimod dans un modèle de myasthénie anti-MuSK. Les Cahiers de Myologie, 2020, 21, pp.21 - 22. ⟨10.1051/myolog/202021004⟩. ⟨hal-03082187⟩
  • Jean-Thomas Vilquin, Serge Braun. Thérapie cellulaire des maladies musculaires Un avenir à l'aune d'une comparaison des progéniteurs. Médecine/Sciences, 2019, Hors-série N°2, 35, pp.7-10. ⟨hal-02356327⟩
  • Sonia Berrih-Aknin, Rozen Le Panse. Thymectomy in myasthenia gravis: when, why, and how?. The Lancet Neurology, 2019, 18 (3), pp.225-226. ⟨10.1016/S1474-4422(18)30467-8⟩. ⟨hal-02357784⟩
  • José Villegas, Alexandra Bayer, Katia Ider, Jacky Bismuth, Frédérique Truffault, et al.. Il-23/Th17 cell pathway: A promising target to alleviate thymic inflammation maintenance in myasthenia gravis. Journal of Autoimmunity, 2019, 98, pp.59-73. ⟨10.1016/j.jaut.2018.11.005⟩. ⟨hal-02357775⟩
  • Mélanie A Cron, Solène Maillard, Frédérique Truffault, Ambra Vittoria Gualeni, Annunziata Gloghini, et al.. Causes and Consequences of miR-150-5p Dysregulation in Myasthenia Gravis. Frontiers in Immunology, 2019, 10, pp.539. ⟨10.3389/fimmu.2019.00539⟩. ⟨hal-02095254⟩
  • Nadine Dragin, Patrice Nancy, José Villegas, Régine Roussin, Rozen Le Panse, et al.. Author Correction: Balance between Estrogens and Proinflammatory Cytokines Regulates Chemokine Production Involved in Thymic Germinal Center Formation. Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-23079-x⟩. ⟨hal-02357790⟩
  • Vuslat Yilmaz, Solène Maillard, Frédérique Truffault, Francis Bolgert, Anthony Behin, et al.. Regulatory B cells in myasthenia gravis are differentially affected by therapies. Annals of Clinical and Translational Neurology, 2018, 5 (11), pp.1408-1414. ⟨10.1002/acn3.645⟩. ⟨hal-01942391⟩
  • Anthony Béhin, Rozen Le Panse. New Pathways and Therapeutic Targets in Autoimmune Myasthenia Gravis. Journal of Neuromuscular Diseases, 2018, 5 (3), pp.265-277. ⟨10.3233/JND-170294⟩. ⟨hal-02357788⟩
  • José Villegas, Angeline Gradolatto, Frédérique Truffault, Régine Roussin, Sonia Berrih-Aknin, et al.. Cultured Human Thymic-Derived Cells Display Medullary Thymic Epithelial Cell Phenotype and Functionality. Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.01663⟩. ⟨hal-02357782⟩
  • Jose Adolfo Villegas, Jérôme van Wassenhove, Rozen Le Panse, Sonia Berrih-Aknin, Nadine Dragin. An imbalance between regulatory T cells and T helper 17 cells in acetylcholine receptor-positive myasthenia gravis patients. Annals of the New York Academy of Sciences, 2018, 1413 (1), pp.154-162. ⟨10.1111/nyas.13591⟩. ⟨hal-02357792⟩
  • Simone Birnbaum, Jean-Yves Hogrel, Raphael Porcher, Pierre Portero, Bernard Clair, et al.. The benefits and tolerance of exercise in myasthenia gravis (MGEX): study protocol for a randomised controlled trial. Trials, 2018, 19, pp.49. ⟨10.1186/s13063-017-2433-2⟩. ⟨hal-01708023⟩
  • Muriel Sudres, Julien Verdier, Frédérique Truffault, Rozen Le Panse, Sonia Berrih-Aknin. Pathophysiological mechanisms of autoimmunity. Annals of the New York Academy of Sciences, 2018, Myasthenia Gravis and Related Disorders II, 1413, pp.59-68. ⟨10.1111/nyas.13560⟩. ⟨hal-01817720⟩
  • Mélanie A Cron, Solène Maillard, Fabien Delisle, Nolwenn Samson, Frédérique Truffault, et al.. Analysis of microRNA expression in the thymus of Myasthenia Gravis patients opens new research avenues. Autoimmunity Reviews, 2018, 17 (6), pp.588-600. ⟨10.1016/j.autrev.2018.01.008⟩. ⟨hal-01844365⟩
  • Christophe Praud, Karine Vauchez, Pascal Zongo, Jean-Thomas Vilquin. Modelling human myoblasts survival upon xenotransplantation into immunodeficient mouse muscle.. Experimental Cell Research, 2018, 364 (2), pp.217-223. ⟨10.1016/j.yexcr.2018.02.011⟩. ⟨hal-02364943⟩
  • Marie Crahes, Marie-Cécile Bories, Jean-Thomas Vilquin, Jean-Pierre Marolleau, Michel Desnos, et al.. Long-Term Engraftment (16 Years) of Myoblasts in a Human Infarcted Heart. Stem Cells Translational Medicine, 2018, 7 (10), pp.705 - 708. ⟨10.1002/sctm.18-0017⟩. ⟨hal-02356366⟩
  • Virginie Mariot, Romain Joubert, Christophe Hourdé, Léonard Feasson, Michael Hanna, et al.. Downregulation of myostatin pathway in neuromuscular diseases may explain challenges of anti-myostatin therapeutic approaches. Nature Communications, 2017, 8 (1), ⟨10.1038/s41467-017-01486-4⟩. ⟨hal-02167071⟩
  • V. Mariot, R. Joubert, C. Hourdé, L. Féasson, M. Hanna, et al.. Reversible endogenous downregulation of myostatin pathway in wasting neuromuscular diseases explains challenges of anti-myostatin therapeutic approaches. Neuromuscular Disorders, 2017, 27, pp.S97-S98. ⟨10.1016/J.NMD.2017.06.026⟩. ⟨hal-03158871⟩
  • V. Mariot, R. Joubert, C. Hourdé, L. Féasson, M. Hanna, et al.. Myostatin expression levels in neuromuscular diseases participates in anti-myostatin clinical failure. Neuromuscular Disorders, 2017, 27, pp.S231. ⟨10.1016/J.NMD.2017.06.490⟩. ⟨hal-03158311⟩
  • Shimrat Mamrut, Nili Avidan, Frédérique Truffault, Elsebeth Staun-Ram, Tarek Sharshar, et al.. Methylome and transcriptome profiling in Myasthenia Gravis monozygotic twins. Journal of Autoimmunity, 2017, 82, pp.62-73. ⟨10.1016/j.jaut.2017.05.005⟩. ⟨hal-03824048⟩
  • Mohamed Attia, Marie Maurer, Marieke Robinet, Fabien Le Grand, Elie Fadel, et al.. Muscle satellite cells are functionally impaired in myasthenia gravis: consequences on muscle regeneration. Acta Neuropathologica, 2017, 134 (6), pp.869 - 888. ⟨10.1007/s00401-017-1754-2⟩. ⟨hal-01682296⟩
  • Angela Lopomo, Sonia Berrih-Aknin. Autoimmune Thyroiditis and Myasthenia Gravis. Frontiers in Endocrinology, 2017, 8, ⟨10.3389/fendo.2017.00169⟩. ⟨hal-03863824⟩
  • Caroline Chong-Nguyen, Karim Wahbi, Vincent Algalarrondo, Henri Marc Bécane, Hélène Radvanyi-Hoffman, et al.. Association Between Mutation Size and Cardiac Involvement in Myotonic Dystrophy Type 1. Circulation: Cardiovascular Genetics, 2017, 10 (3), ⟨10.1161/CIRCGENETICS.116.001526⟩. ⟨hal-03830988⟩
  • Marieke Robinet, Solène Maillard, Mélanie A. Cron, Sonia Berrih-Aknin, Rozen Le Panse. Review on Toll-Like Receptor Activation in Myasthenia Gravis: Application to the Development of New Experimental Models. Clinical Reviews in Allergy and Immunology, 2017, 52 (1), pp.133-147. ⟨10.1007/s12016-016-8549-4⟩. ⟨hal-01321397⟩
  • Nadine Dragin, Rozen Le Panse, Sonia Berrih-Aknin. Prédisposition aux pathologies auto-immmunes. Médecine/Sciences, 2017, 33 (2), pp.169-175. ⟨10.1051/medsci/20173302012⟩. ⟨hal-03824050⟩
  • Nadine Dragin, Patrice Nancy, José Villegas, Régine Roussin, Rozen Le Panse, et al.. Balance between Estrogens and Proinflammatory Cytokines Regulates Chemokine Production Involved in Thymic Germinal Center Formation. Scientific Reports, 2017, 7, pp.7970. ⟨10.1038/s41598-017-08631-5⟩. ⟨hal-01580123⟩
  • Muriel Sudres, Marie Maurer, Marieke Robinet, Jacky Bismuth, Frédérique Truffault, et al.. Preconditioned mesenchymal stem cells treat myasthenia gravis in a humanized preclinical model. JCI Insight, 2017, 2 (7), pp.1442-4. ⟨10.1172/jci.insight.89665⟩. ⟨hal-01510169⟩
  • Marieke Robinet, Bérengère Villeret, Solène Maillard, Mélanie A. Cron, Sonia Berrih-Aknin, et al.. Use of Toll-Like Receptor Agonists to Induce Ectopic Lymphoid Structures in Myasthenia Gravis Mouse Models. Frontiers in Immunology, 2017, 8, pp.1029. ⟨10.3389/fimmu.2017.01029⟩. ⟨hal-01585119⟩
  • Jean-Thomas Vilquin, Jessy Etienne. Thérapies cellulaires des cardiopathies. Médecine/Sciences, 2016, 32, pp.30-39. ⟨10.1051/medsci/201632s209⟩. ⟨hal-03824005⟩
  • Nadine Dragin, Jacky Bismuth, Géraldine Cizeron-Clairac, Maria Grazia Biferi, Claire Berthault, et al.. Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases.. Journal of Clinical Investigation, 2016, 126 (4), pp.1525-37. ⟨10.1172/JCI81894⟩. ⟨hal-01310502⟩
  • J.M. Weiss, M Robinet, R Aricha, P Cufi, Bérengère Villeret, et al.. Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis. Oncotarget, 2016, 7 (7), pp.7550-7562. ⟨hal-01427126⟩
  • Frédérique Truffault, Vincent de Montpreville, Bruno Eymard, Tarek Sharshar, Rozen Le Panse, et al.. Thymic Germinal Centers and Corticosteroids in Myasthenia Gravis: an Immunopathological Study in 1035 Cases and a Critical Review. Clinical Reviews in Allergy and Immunology, 2016, pp.1-17. ⟨10.1007/s12016-016-8558-3⟩. ⟨hal-01338400⟩
  • Julia Miriam Weiss, Marieke Robinet, Revital Aricha, Perrine Cufi, Bérengère Villeret, et al.. Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis. OncoTargets and Therapy, 2016, 7 (7), pp.7550-7552. ⟨hal-01293674⟩
  • Erdem Tuzun, Sonia Berrih-Aknin, Talma Brenner, Linda Kusner, Rozen Le Panse, et al.. Guidelines for standard preclinical experiments in the mouse model of myasthenia gravis induced by acetylcholine receptor immunization. Experimental Neurology, 2015, 270, pp.11-17. ⟨10.1016/j.expneurol.2015.02.009⟩. ⟨hal-03442103⟩
  • Gaelle Bruneteau, Stéphanie Bauché, Jose-Luis Gonzalez de Aguilar, Guy Brochier, Nathalie Mandjee, et al.. Endplate denervation correlates with Nogo-A muscle expression in amyotrophic lateral sclerosis patients. Annals of Clinical and Translational Neurology, 2015, 2 (4), pp.362-372. ⟨10.1002/acn3.179⟩. ⟨hal-01118997⟩
  • Kathleen Vrolix, Judith Fraussen, Mario Losen, Jo Stevens, Konstantinos Lazaridis, et al.. Clonal heterogeneity of thymic B cells from early-onset myasthenia gravis patients with antibodies against the acetylcholine receptor. Journal of Autoimmunity, 2014, 52, pp.101-112. ⟨10.1016/j.jaut.2013.12.008⟩. ⟨hal-03442084⟩
  • Perrine Cufi, Patrick Soussan, Frédérique Truffault, Rachid Fetouchi, Marieke Robinet, et al.. Thymoma-associated myasthenia gravis: On the search for a pathogen signature. Journal of Autoimmunity, 2014, 52, pp.29-35. ⟨10.1016/j.jaut.2013.12.018⟩. ⟨hal-03442082⟩
  • Perrine Cufi, Nadine Dragin, Nathalie Ruhlmann, Julia Miriam Weiss, Elie Fadel, et al.. Central role of interferon-beta in thymic events leading to myasthenia gravis. Journal of Autoimmunity, 2014, 52 (SI), pp.44-52. ⟨10.1016/j.jaut.2013.12.016⟩. ⟨hal-01514459⟩
  • Nili Avidan, Rozen Le Panse, Sonia Berrih-Aknin, Ariel Miller. Genetic basis of myasthenia gravis – A comprehensive review. Journal of Autoimmunity, 2014, 52, pp.146-153. ⟨10.1016/j.jaut.2013.12.001⟩. ⟨hal-03442105⟩
  • Sonia Berrih-Aknin, Rozen Le Panse. Myasthenia gravis: A comprehensive review of immune dysregulation and etiological mechanisms. Journal of Autoimmunity, 2014, 52, pp.90-100. ⟨10.1016/j.jaut.2013.12.011⟩. ⟨hal-03442104⟩
  • S. Berrih-Aknin, R. Le Panse. Myasthénie et auto-anticorps : physiopathologie des différentes entités. La Revue de Médecine Interne, 2014, 35 (7), pp.413-420. ⟨10.1016/j.revmed.2013.09.012⟩. ⟨hal-03442106⟩
  • Nili Avidan, Rozen Le Panse, Hanne Harbo, Pia Bernasconi, Konstantinos Poulas, et al.. VAV 1 and BAFF , via NF κB pathway, are genetic risk factors for myasthenia gravis. Annals of Clinical and Translational Neurology, 2014, 1 (5), pp.329-339. ⟨10.1002/acn3.51⟩. ⟨inserm-04284319⟩
  • Tanel Punga, Rozen Panse, Mats Andersson, Frédérique Truffault, Sonia Berrih‐aknin, et al.. Circulating mi RNA s in myasthenia gravis: miR‐150‐5p as a new potential biomarker. Annals of Clinical and Translational Neurology, 2014, 1 (1), pp.49-58. ⟨10.1002/acn3.24⟩. ⟨hal-03442080⟩
  • Sonia Berrih-Aknin, Samia Ragheb, Rozen Le Panse, Robert Lisak. Ectopic germinal centers, BAFF and anti-B-cell therapy in myasthenia gravis. Autoimmunity Reviews, 2013, 12 (9), pp.885-893. ⟨10.1016/j.autrev.2013.03.011⟩. ⟨hal-03442110⟩
  • Paola Cavalcante, Perrine Cufi, Renato Mantegazza, Sonia Berrih-Aknin, Pia Bernasconi, et al.. Etiology of myasthenia gravis: Innate immunity signature in pathological thymus. Autoimmunity Reviews, 2013, 12 (9), pp.863-874. ⟨10.1016/j.autrev.2013.03.010⟩. ⟨hal-03442109⟩
  • Cyril Catelain, Stéphanie Riveron, Aurélie Papadopoulos, Nathalie Mougenot, Adeline Jacquet, et al.. Myoblasts and Embryonic Stem Cells Differentially Engraft in a Mouse Model of Genetic Dilated Cardiomyopathy. Molecular Therapy, 2013, 21 (5), pp.1064-1075. ⟨10.1038/mt.2013.15⟩. ⟨hal-03823994⟩
  • Julia Miriam Weiss, Perrine Cufi, Jacky Bismuth, Bruno Eymard, Elie Fadel, et al.. SDF-1/CXCL12 recruits B cells and antigen-presenting cells to the thymus of autoimmune myasthenia gravis patients. Immunobiology, 2013, 218 (3), pp.373-381. ⟨10.1016/j.imbio.2012.05.006⟩. ⟨hal-03442086⟩
  • Felix Friedrich, Gilles Dilanian, Patricia Khattar, Denise Juhr, Lucie Gueneau, et al.. A novel genetic variant in the transcription factor Islet‐1 exerts gain of function on myocyte enhancer factor 2C promoter activity. European Journal of Heart Failure, 2013, 15 (3), pp.267-276. ⟨10.1093/eurjhf/hfs178⟩. ⟨hal-03824016⟩
  • Perrine Cufi, Nadine Dragin, Julia Miriam Weiss, Pilar Martinez-Martinez, Marc de Baets, et al.. Implication of double-stranded RNA signaling in the etiology of autoimmune myasthenia gravis. Annals of Neurology, 2013, 73 (2), pp.281-293. ⟨10.1002/ana.23791⟩. ⟨hal-03442085⟩
  • Angeline Gradolatto, Dani Nazzal, Maria Foti, Jacky Bismuth, Frederique Truffault, et al.. Defects of immunoregulatory mechanisms in myasthenia gravis: role of IL-17. Annals of the New York Academy of Sciences, 2012, 1274 (1), pp.40-47. ⟨10.1111/j.1749-6632.2012.06791.x⟩. ⟨hal-03442113⟩
  • Jean-Thomas Vilquin. Converting Pathological Cells to Therapeutic Ones: An Odyssey Through Pluripotency. Molecular Therapy, 2012, 20 (11), pp.2012-2014. ⟨10.1038/mt.2012.219⟩. ⟨hal-03824021⟩
  • R. Hage Hassan, I. Hainault, J.-T. Vilquin, C. Samama, F. Lasnier, et al.. Endoplasmic reticulum stress does not mediate palmitate-induced insulin resistance in mouse and human muscle cells. Diabetologia, 2012, 55 (1), pp.204-214. ⟨10.1007/s00125-011-2328-9⟩. ⟨hal-03824022⟩
  • R. Hage Hassan, I. Hainault, J.-T. Vilquin, C. Samama, F. Lasnier, et al.. Endoplasmic reticulum stress does not mediate palmitate-induced insulin resistance in mouse and human muscle cells. Diabetologia, 2012, 55 (1), pp.204-214. ⟨10.1007/s00125-011-2328-9⟩. ⟨hal-02450935⟩
  • Paola Cavalcante, Rozen Le Panse, Sonia Berrih-Aknin, Lorenzo Maggi, Carlo Antozzi, et al.. The thymus in myasthenia gravis: Site of “innate autoimmunity”?. Muscle & nerve. Supplement., 2011, 44 (4), pp.467-484. ⟨10.1002/mus.22103⟩. ⟨hal-03442111⟩
  • Patricia Khattar, Felix Friedrich, Gisèle Bonne, Lucie Carrier, Thomas Eschenhagen, et al.. Distinction Between Two Populations of Islet-1-Positive Cells in Hearts of Different Murine Strains. Stem Cells and Development, 2011, 20 (6), pp.1043-1052. ⟨10.1089/scd.2010.0374⟩. ⟨hal-03824036⟩
  • Kathleen Vrolix, Erik Niks, Rozen Le Panse, Monique van Ostaijen-ten Dam, Anne-Hilde Muris, et al.. Reduced thymic expression of ErbB receptors without auto-antibodies against synaptic ErbB in myasthenia gravis. Journal of Neuroimmunology, 2011, 232 (1-2), pp.158-165. ⟨10.1016/j.jneuroim.2010.10.024⟩. ⟨hal-03442087⟩
  • Elisa Negroni, Denis Vallese, Jean-Thomas Vilquin, Gillian Butler-Browne, Vincent Mouly, et al.. Current advances in cell therapy strategies for muscular dystrophies. Expert Opinion on Biological Therapy, 2011, 11 (2), pp.157-176. ⟨10.1517/14712598.2011.542748⟩. ⟨hal-03824033⟩
  • Jean-Thomas Vilquin, Cyril Catelain, Karine Vauchez. Cell therapy for muscular dystrophies. Current Opinion in Organ Transplantation, 2011, 16 (6), pp.640-649. ⟨10.1097/MOT.0b013e32834cfb70⟩. ⟨hal-03824031⟩
  • Séverine Lecourt, Jean-Pierre Marolleau, Olivia Fromigué, Karine Vauchez, Rina Andriamanalijaona, et al.. Characterization of distinct mesenchymal-like cell populations from human skeletal muscle in situ and in vitro. Experimental Cell Research, 2010, 316 (15), pp.2513-2526. ⟨10.1016/j.yexcr.2010.04.020⟩. ⟨hal-03824039⟩
  • Rozen Le Panse, Jacky Bismuth, Géraldine Cizeron-Clairac, Julia Miriam Weiss, Perrine Cufi, et al.. Thymic remodeling associated with hyperplasia in myasthenia gravis. Autoimmunity, 2010, 43 (5-6), pp.401-412. ⟨10.3109/08916930903563491⟩. ⟨hal-03442112⟩
  • Karine Vauchez, Jean-Pierre Marolleau, Michel Schmid, Patricia Khattar, Alain Chapel, et al.. Aldehyde Dehydrogenase Activity Identifies a Population of Human Skeletal Muscle Cells With High Myogenic Capacities. Molecular Therapy, 2009, 17 (11), pp.1948-1958. ⟨10.1038/mt.2009.204⟩. ⟨hal-03824042⟩
  • Sonia Berrih-Aknin, Nathalie Ruhlmann, Jacky Bismuth, Géraldine Cizeron-Clairac, Einat Zelman, et al.. CCL21 overexpressed on lymphatic vessels drives thymic hyperplasia in myasthenia. Annals of Neurology, 2009, 66 (4), pp.521-531. ⟨10.1002/ana.21628⟩. ⟨hal-03442088⟩
  • C Baligand, K Vauchez, M Fiszman, J-T Vilquin, P Carlier. Discrepancies between the fate of myoblast xenograft in mouse leg muscle and NMR label persistency after loading with Gd-DTPA or SPIOs. Gene Therapy, 2009, 16 (6), pp.734-745. ⟨10.1038/gt.2009.12⟩. ⟨hal-03824059⟩
  • R. Andriamanalijaona, E. Duval, M. Raoudi, S. Lecourt, J.T. Vilquin, et al.. Differentiation potential of human muscle-derived cells towards chondrogenic phenotype in alginate beads culture. Osteoarthritis and Cartilage, 2008, 16 (12), pp.1509-1518. ⟨10.1016/j.joca.2008.04.018⟩. ⟨hal-03824337⟩
  • Géraldine Cizeron-Clairac, Rozen Le Panse, Mélinée Frenkian-Cuvelier, Amel Meraouna, Frédérique Truffault, et al.. Thymus and Myasthenia Gravis: What can we learn from DNA microarrays?. Journal of Neuroimmunology, 2008, 201-202, pp.57-63. ⟨10.1016/j.jneuroim.2008.06.028⟩. ⟨hal-03442089⟩
  • Christophe Praud, K. Vauchez, A. Lombes, M. Fiszman, J.-T. Vilquin. Myoblast Xenotransplantation as a Tool to Evaluate the Appropriateness of Nanoparticular versus Cellular Trackers. Cell Transplantation, 2008, 17 (9), pp.1035-1043. ⟨10.3727/096368908786991588⟩. ⟨hal-03224198⟩
  • C. Praud, K. Vauchez, A. Lombes, M. Fiszman, J.-T. Vilquin. Myoblast Xenotransplantation as a Tool to Evaluate the Appropriateness of Nanoparticular versus Cellular Trackers. Cell Transplantation, 2008, 17 (9), pp.1035-1043. ⟨10.3727/096368908786991588⟩. ⟨hal-03824065⟩
  • Rozen Le Panse, Géraldine Cizeron-Clairac, Mélinée Cuvelier, Frédérique Truffault, Jacky Bismuth, et al.. Regulatory and Pathogenic Mechanisms in Human Autoimmune Myasthenia Gravis. Annals of the New York Academy of Sciences, 2008, 1132 (1), pp.135-142. ⟨10.1196/annals.1405.019⟩. ⟨hal-03442114⟩
  • Philippe Menasché, Ottavio Alfieri, Stefan Janssens, William Mckenna, Hermann Reichenspurner, et al.. The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) Trial. Circulation, 2008, 117 (9), pp.1189-1200. ⟨10.1161/CIRCULATIONAHA.107.734103⟩. ⟨hal-03824067⟩
  • Sophie Le Ricousse-Roussanne, Jerome Larghero, Jean-Marc Zini, Veronique Barateau, Philippe Foubert, et al.. Ex vivo generation of mature and functional human smooth muscle cells differentiated from skeletal myoblasts. Experimental Cell Research, 2007, 313 (7), pp.1337-1346. ⟨10.1016/j.yexcr.2007.01.022⟩. ⟨hal-03824345⟩
  • Adi Gilboa-Geffen, Paul Lacoste, Lilach Soreq, Geraldine Cizeron-Clairac, Rozen Le Panse, et al.. The thymic theme of acetylcholinesterase splice variants in myasthenia gravis. Blood, 2007, 109 (10), pp.4383-4391. ⟨10.1182/blood-2006-07-033373⟩. ⟨hal-03442090⟩
  • Rozen Le Panse, Géraldine Cizeron-Clairac, Jacky Bismuth, Sonia Berrih-Aknin. Microarrays Reveal Distinct Gene Signatures in the Thymus of Seropositive and Seronegative Myasthenia Gravis Patients and the Role of CC Chemokine Ligand 21 in Thymic Hyperplasia. Journal of Immunology, 2006, 177 (11), pp.7868-7879. ⟨10.4049/jimmunol.177.11.7868⟩. ⟨hal-03442091⟩
  • Amel Meraouna, Geraldine Cizeron-Clairac, Rozen Le Panse, Jacky Bismuth, Frederique Truffault, et al.. The chemokine CXCL13 is a key molecule in autoimmune myasthenia gravis. Blood, 2006, 108 (2), pp.432-440. ⟨10.1182/blood-2005-06-2383⟩. ⟨hal-02970806⟩
  • Albert Hagège, Jean-Pierre Marolleau, Jean-Thomas Vilquin, Armelle Alhéritière, Séverine Peyrard, et al.. Skeletal Myoblast Transplantation in Ischemic Heart Failure. Circulation, 2006, 114 (1_supplement), ⟨10.1161/CIRCULATIONAHA.105.000521⟩. ⟨hal-03824070⟩
  • Jean-Thomas Vilquin, Philippe Rosset. Mesenchymal stem cells in bone and cartilage repair: current status. Regenerative Medicine, 2006, 1 (4), pp.589-604. ⟨10.2217/17460751.1.4.589⟩. ⟨hal-03824341⟩
  • Emmanuel Messas, Alain Bel, Miguel Cortes Morichetti, Claire Carrion, Marc Handschumacher, et al.. Autologous Myoblast Transplantation for Chronic Ischemic Mitral Regurgitation. Journal of the American College of Cardiology, 2006, 47 (10), pp.2086-2093. ⟨10.1016/j.jacc.2005.12.063⟩. ⟨hal-03824071⟩
  • J-T Vilquin, J-P Marolleau, S Sacconi, I Garcin, M-N Lacassagne, et al.. Normal growth and regenerating ability of myoblasts from unaffected muscles of facioscapulohumeral muscular dystrophy patients. Gene Therapy, 2005, 12 (22), pp.1651-1662. ⟨10.1038/sj.gt.3302565⟩. ⟨hal-03824077⟩
  • Camille Brasselet, Miguel Cortes Morichetti, Emmanuel Messas, Claire Carrion, Alvine Bissery, et al.. Skeletal myoblast transplantation through a catheter-based coronary sinus approach: an effective means of improving function of infarcted myocardium. European Heart Journal, 2005, 26 (15), pp.1551-1556. ⟨10.1093/eurheartj/ehi151⟩. ⟨hal-03824360⟩
  • Sandrine Poëa-Guyon, Premkumar Christadoss, Rozen Le Panse, Thierry Guyon, Marc de Baets, et al.. Effects of Cytokines on Acetylcholine Receptor Expression: Implications for Myasthenia Gravis. Journal of Immunology, 2005, 174 (10), pp.5941-5949. ⟨10.4049/jimmunol.174.10.5941⟩. ⟨hal-02522187⟩
  • R Le Panse, S Berrih-Aknin. Thymic myoid cells protect thymocytes from apoptosis and modulate their differentiation: implication of the ERK and Akt signaling pathways. Cell Death and Differentiation, 2005, 12 (5), pp.463-472. ⟨10.1038/sj.cdd.4401611⟩. ⟨hal-03442092⟩
  • Agnès Maurel, Kasra Azarnoush, Laurent Sabbah, Nicolas Vignier, Marc Le Lorc'H, et al.. Can Cold or Heat Shock Improve Skeletal Myoblast Engraftment in Infarcted Myocardium?. Transplantation, 2005, 80 (5), pp.660-665. ⟨10.1097/01.tp.0000172178.35488.31⟩. ⟨hal-03824075⟩
  • Julia Pouly, Albert Hagège, Jean-Thomas Vilquin, Alvine Bissery, Andrée Rouche, et al.. Does the Functional Efficacy of Skeletal Myoblast Transplantation Extend to Nonischemic Cardiomyopathy?. Circulation, 2004, 110 (12), pp.1626-1631. ⟨10.1161/01.CIR.0000142861.55862.15⟩. ⟨hal-03824364⟩
  • Onnik Agbulut, Susanne Vandervelde, Nawwar Al Attar, Jérôme Larghero, Said Ghostine, et al.. Comparison of human skeletal myoblasts and bone marrow-derived CD133+progenitors for the repair of infarcted myocardium. Journal of the American College of Cardiology, 2004, 44 (2), pp.458-463. ⟨10.1016/j.jacc.2004.03.083⟩. ⟨hal-03824372⟩
  • Rozen Panse-Ruskoné, Sonia Berrih-Aknin. Human Myoid Cells Protect Thymocytes from Apoptosis. Annals of the New York Academy of Sciences, 2003, 998 (1), pp.266-269. ⟨10.1196/annals.1254.028⟩. ⟨hal-03442116⟩
  • Bertrand Léobon, Isabelle Garcin, Philippe Menasché, Jean-Thomas Vilquin, Etienne Audinat, et al.. Myoblasts transplanted into rat infarcted myocardium are functionally isolated from their host. Proceedings of the National Academy of Sciences of the United States of America, 2003, 100 (13), pp.7808-7811. ⟨10.1073/pnas.1232447100⟩. ⟨hal-03824081⟩
  • Philippe Menasché, Albert Hagège, Jean-Thomas Vilquin, Michel Desnos, Eric Abergel, et al.. Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction. Journal of the American College of Cardiology, 2003, 41 (7), pp.1078-1083. ⟨10.1016/s0735-1097(03)00092-5⟩. ⟨hal-03824083⟩
  • N Alattar, C Carrion, S Ghostine, I Garcin, J Vilquin, et al.. Long-term (1 year) functional and histological results of autologous skeletal muscle cells transplantation in rat. Cardiovascular Research, 2003, 58 (1), pp.142-148. ⟨10.1016/s0008-6363(02)00790-3⟩. ⟨hal-03824087⟩
  • Sylvie Besse, Valérie Allamand, Jean-Thomas Vilquin, Zhenlin Li, Christophe Poirier, et al.. Spontaneous muscular dystrophy caused by a retrotransposal insertion in the mouse laminin α2 chain gene. Neuromuscular Disorders, 2003, 13 (3), pp.216-222. ⟨10.1016/s0960-8966(02)00278-x⟩. ⟨hal-03824380⟩
  • L.T. Guo, X.U. Zhang, W. Kuang, H. Xu, L.A. Liu, et al.. Laminin α2 deficiency and muscular dystrophy; genotype-phenotype correlation in mutant mice. Neuromuscular Disorders, 2003, 13 (3), pp.207-215. ⟨10.1016/s0960-8966(02)00266-3⟩. ⟨hal-03824384⟩
  • Albert Hagège, Claire Carrion, Philippe Menasché, Jean-Thomas Vilquin, Denis Duboc, et al.. Viability and differentiation of autologous skeletal myoblast grafts in ischaemic cardiomyopathy. The Lancet, 2003, 361 (9356), pp.491-492. ⟨10.1016/S0140-6736(03)12458-0⟩. ⟨hal-03824092⟩
  • Rozen Le Panse, Louis Dubertret, Bernard Coulomb. p38 Mitogen-activated Protein Kinase Activation by Ultraviolet A Radiation in Human Dermal Fibroblasts¶. Photochemistry and Photobiology, 2003, 78 (2), pp.168. <a target="_blank" href="https://dx.doi.org/10.1562/0031-8655(2003)0782.0.co;2">⟨10.1562/0031-8655(2003)0782.0.co;2⟩. ⟨hal-03442095⟩
  • Bruno Pitard, Hélène Pollard, Onnik Agbulut, Olivier Lambert, Jean-Thomas Vilquin, et al.. A Nonionic Amphiphile Agent Promotes Gene Delivery In Vivo to Skeletal and Cardiac Muscles. Human Gene Therapy, 2002, 13 (14), pp.1767-1775. ⟨10.1089/104303402760293592⟩. ⟨hal-03824393⟩
  • Daniel Skuk, Jean Thomas Vilquin, Jacques Tremblay. Experimental and therapeutic approaches to muscular dystrophies. Current Opinion in Neurology, 2002, 15 (5), pp.563-569. ⟨10.1097/00019052-200210000-00007⟩. ⟨hal-03824399⟩
  • Albert Hagège, Jean-Thomas Vilquin, Patrick Bruneval, Philippe Menasché. Regeneration of the myocardium: a new role in the treatment of ischemic heart disease?. Hypertension, 2001, 38 (6), pp.1413-1415. ⟨10.1161/hy1201.099618⟩. ⟨hal-03824403⟩
  • Bruno Pouzet, Saïd Ghostine, Jean-Thomas Vilquin, Isabelle Garcin, Marcio Scorsin, et al.. Is Skeletal Myoblast Transplantation Clinically Relevant in the Era of Angiotensin-Converting Enzyme Inhibitors?. Circulation, 2001, 104 (suppl 1), pp.I-223-I-228. ⟨10.1161/hc37t1.094593⟩. ⟨hal-03824409⟩
  • Jt Vilquin, Pf Kennel, M Paturneau-Jouas, P Chapdelaine, N Boissel, et al.. Electrotransfer of naked DNA in the skeletal muscles of animal models of muscular dystrophies. Gene Therapy, 2001, 8 (14), pp.1097-1107. ⟨10.1038/sj.gt.3301484⟩. ⟨hal-03824098⟩
  • Bruno Pouzet, Jean-Thomas Vilquin, Albert Hagège, Marcio Scorsin, Emmanuel Messas, et al.. Factors affecting functional outcome after autologous skeletal myoblast transplantation. Annals of Thoracic Surgery, 2001, 71 (3), pp.844-851. ⟨10.1016/s0003-4975(00)01785-9⟩. ⟨hal-03824418⟩
  • Philippe Menasché, Albert Hagège, Marcio Scorsin, Bruno Pouzet, Michel Desnos, et al.. Myoblast transplantation for heart failure. The Lancet, 2001, 357 (9252), pp.279-280. ⟨10.1016/S0140-6736(00)03617-5⟩. ⟨hal-03824102⟩
  • B. Pouzet, J.-T. Vilquin, A. Hagege, M. Scorsin, E. Messas, et al.. Intramyocardial Transplantation of Autologous Myoblasts : Can Tissue Processing Be Optimized?. Circulation, 2000, 102 (Supplement 3), pp.III-210-III-215. ⟨10.1161/01.cir.102.suppl_3.iii-210⟩. ⟨hal-03824428⟩
  • B. Pouzet, J.-T. Vilquin, A. Hagege, M. Scorsin, E. Messas, et al.. Intramyocardial Transplantation of Autologous Myoblasts : Can Tissue Processing Be Optimized?. Circulation, 2000, 102 (Supplement 3), pp.III-210-III-215. ⟨10.1161/01.cir.102.suppl_3.iii-210⟩. ⟨hal-03824106⟩
  • Daniel Skuk, Denis Furling, Jean-Pierre Bouchard, Marlyne Goulet, Brigitte Roy, et al.. Transplantation of Human Myoblasts in SCID Mice as a Potential Muscular Model for Myotonic Dystrophy. Journal of Neuropathology and Experimental Neurology, 1999, 58 (9), pp.921-931. ⟨10.1097/00005072-199909000-00003⟩. ⟨hal-03824113⟩
  • J-T Vilquin, B Guérette, J Puymirat, D Yaffe, F Tomé, et al.. Myoblast transplantations lead to the expression of the laminin α2 chain in normal and dystrophic (dy/dy) mouse muscles. Gene Therapy, 1999, 6 (5), pp.792-800. ⟨10.1038/sj.gt.3300889⟩. ⟨hal-03824110⟩
  • J.-T. Vilquin, V. Brussee, I. Asselin, I. Kinoshita, M. Gingras, et al.. Evidence ofmdx mouse skeletal muscle fragility in vivo by eccentric running exercise. Muscle & Nerve, 1998, 21 (5), pp.567-576. <a target="_blank" href="https://dx.doi.org/10.1002/(sici)1097-4598(199805)21:53.0.co;2-6">⟨10.1002/(sici)1097-4598(199805)21:53.0.co;2-6⟩. ⟨hal-03824116⟩
  • Hijiri Ito, Jean-Thomas Vilquin, Daniel Skuk, Brigitte Roy, Marlyne Goulet, et al.. Myoblast transplantation in non-dystrophic dog. Neuromuscular Disorders, 1998, 8 (2), pp.95-110. ⟨10.1016/s0960-8966(97)00148-x⟩. ⟨hal-03824439⟩
  • Catherine Hazzalin, Rozen Le Panse, Eva Cano, Louis Mahadevan. Anisomycin Selectively Desensitizes Signalling Components Involved in Stress Kinase Activation and fos and jun Induction. Molecular and Cellular Biology, 1998, 18 (4), pp.1844-1854. ⟨10.1128/MCB.18.4.1844⟩. ⟨hal-03442096⟩
  • B. Guérette, J. Vilquin, M. Gingras, C. Gravel, K. Wood, et al.. Prevention of Immune Reactions Triggered by First-Generation Adenoviral Vectors by Monoclonal Antibodies and CTLA4Ig. Human Gene Therapy, 1996, 7 (12), pp.1455-1463. ⟨10.1089/hum.1996.7.12-1455⟩. ⟨hal-03824150⟩
  • I. Kinoshita, J.T. Vilquin, R. Roy, J.P. Tremblay. Successive injections in MDX mice of myoblasts grown with bFGF. Neuromuscular Disorders, 1996, 6 (3), pp.187-193. ⟨10.1016/0960-8966(96)00004-1⟩. ⟨hal-03824447⟩
  • Ikuo Kinoshita, Jean-Thomas Vilquin, J. Tremblay. Mechanism of increasing dystrophin-positive myofibers by myoblast transplantation: study using mdx/β-galactosidase transgenic mice. Acta Neuropathologica, 1996, 91 (5), pp.489-493. ⟨10.1007/s004010050456⟩. ⟨hal-03824146⟩
  • Rozen Panse, Brigitte Bouchard, Corinne Lebreton, Bernard Coulomb. Modulation of keratinocyte growth factor (KGF) mRNA expression in human dermal fibroblasts grown in monolayer or within a collagen matrix. Experimental Dermatology, 1996, 5 (2), pp.108-114. ⟨10.1111/j.1600-0625.1996.tb00103.x⟩. ⟨hal-03442099⟩
  • J Vilquin, I Kinoshita, B Roy, M Goulet, E Engvall, et al.. Partial laminin alpha2 chain restoration in alpha2 chain-deficient dy/dy mouse by primary muscle cell culture transplantation.. Journal of Cell Biology, 1996, 133 (1), pp.185-197. ⟨10.1083/jcb.133.1.185⟩. ⟨hal-03824121⟩
  • R. Le Panse, V. Mitev, Louis L. Houdebine, B. Coulomb. Protein kinase C-independent activation of mitogen-activated protein kinase by epidermal growth factor in skin fibroblasts. European Journal of Pharmacology, 1996, 307, pp.339-345. ⟨hal-02688152⟩
  • J Vilquin, E Wagner, I Kinoshita, R Roy, J Tremblay. Successful histocompatible myoblast transplantation in dystrophin-deficient mdx mouse despite the production of antibodies against dystrophin.. Journal of Cell Biology, 1995, 131 (4), pp.975-988. ⟨10.1083/jcb.131.4.975⟩. ⟨hal-03824128⟩
  • J.T. Vilquin, I. Kinoshita, R. Roy, J.P. Tremblay. Cyclophosphamide immunosuppression does not permit successful myoblast allotransplantation in mouse. Neuromuscular Disorders, 1995, 5 (6), pp.511-517. ⟨10.1016/0960-8966(95)00011-b⟩. ⟨hal-03824453⟩
  • Jean-Thomas Vilquin, Benoît Guérette, Ikuo Kinoshita, Brigitte Roy, Marlyne Goulet, et al.. FK506 Immunosuppression to Control the Immune Reactions Triggered by First-Generation Adenovirus-Mediated Gene Transfer. Human Gene Therapy, 1995, 6 (11), pp.1391-1401. ⟨10.1089/hum.1995.6.11-1391⟩. ⟨hal-03824124⟩
  • Isabelle Asselin, Martine Tremblay, Jean-Thomas Vilquin, Benoît Guérette, R. Roy, et al.. Quantification of normal dystrophin mRNA following myoblast transplantation in mdx mice. Muscle & Nerve, 1995, 18 (9), pp.980-986. ⟨10.1002/mus.880180909⟩. ⟨hal-03824455⟩
  • Ikuo Kinoshita, Jean-Thomas Vilquin, Jacques Tremblay. Pretreatment of myoblast cultures with basic fibroblast growth factor increases the efficacy of their transplantation in mdx mice. Muscle & Nerve, 1995, 18 (8), pp.834-841. ⟨10.1002/mus.880180806⟩. ⟨hal-03824143⟩
  • P.F. Kennel, J.T. Vilquin, S. Braun, P. Fonteneau, J.M. Warter, et al.. Myasthenia Gravis: Comparative Autoantibody Assays Using Human Muscle, TE671, and Glucocorticoid-Treated TE671 Cells as Sources of Antigen. Clinical immunology and immunopathology, 1995, 74 (3), pp.293-296. ⟨10.1006/clin.1995.1042⟩. ⟨hal-03824130⟩
  • Isabelle Asselin, Jean Thomas Vilquin, Jacques Tremblay, Benoǐt Guérette, Raynald Roy. Lymphocyte infiltration following allo-and xenomyoblast transplantation in mdx mice. Muscle & Nerve, 1995, 18 (1), pp.39-51. ⟨10.1002/mus.880180107⟩. ⟨hal-03824468⟩
  • V. Mitev, R. Le Panse, B. Coulomb, L. Miteva, Louis L. Houdebine. Epidermal growth factor stimulates mitogen-activated protein kinase by a PKC-dependent pathway in human keratinocytes. Biochemical and Biophysical Research Communications, 1995, 208 (1), pp.245-252. ⟨hal-02704693⟩
  • Ikuo Kinoshita, Jean-Thomas Vilquin, Benoǐt Guérette, Isabelle Asselin, Raynald Roy, et al.. Very efficient myoblast allotransplantation in mice under FK506 immunosuppression. Muscle & Nerve, 1994, 17 (12), pp.1407-1415. ⟨10.1002/mus.880171210⟩. ⟨hal-03824133⟩
  • R. Lepanse, V. Mitev, C. Lebreton, B. Coulomb. Modulation of Epidermal Growth Factor and Keratinocyte Growth Factor Effects on Human Keratinocyte Growth by Protein Kinase C Inhibitor, GF 109203X: Comparison to Fibroblast Growth Modulation. Biochemical and Biophysical Research Communications, 1994, 204 (3), pp.1081-1087. ⟨10.1006/bbrc.1994.2573⟩. ⟨hal-03442100⟩
  • J.-T. Vilquin, S. Braun, P. Labouret, G. Zuber, C. Tranchant, et al.. Specific effect of corticoids on acetylcholine receptor expression in rat skeletal muscle cell cultures. Journal of Neuroscience Research, 1992, 31 (2), pp.285-293. ⟨10.1002/jnr.490310209⟩. ⟨hal-03824136⟩
  • Serge Braun, Christine Tranchant, Jean-Thomas Vilquin, Pascale Labouret, Jean-Marie Warter, et al.. Stimulating effects of prednisolone on acetylcholine receptor expression and myogenesis in primary culture of newborn rat muscle cells. Journal of the Neurological Sciences, 1989, 92 (2-3), pp.119-131. ⟨10.1016/0022-510x(89)90130-5⟩. ⟨hal-03824139⟩

Communications dans un congrès25 document

  • A. Merlet, E. Lacène, I. Nelson, G. Brochier, C. Labasse, et al.. P338 Clinical, morphological, and proteomic features of patients suspected of X-linked myopathy with excessive autophagy (XMEA). 28th International Annual Congress of the World Muscle Society, Oct 2023, Charleston SC, United States. pp.S99, ⟨10.1016/j.nmd.2023.07.136⟩. ⟨hal-04280238⟩
  • V. Decostre, C. Chikhaoui, C. Vigouroux, A. Behin, G. Bassez, et al.. VP429 Impaired skeletal muscle strength in adult patients with laminopathies. 28th International Annual Congress of the World Muscle Society, Oct 2023, Charleston SC, United States. pp.S159-S160, ⟨10.1016/j.nmd.2023.07.370⟩. ⟨hal-04280272⟩
  • Alexandra Bayer Wildberger, Natalia Pinzon, Axel You, Frédérique Truffault, Aurélien Corneau, et al.. Cell therapy approaches for Myasthenia gravis: in vitro and in vivo evaluations of conditioned mesenchymal stem cells. 12th Japanese-French Workshop, Sep 2022, Giverny, France. ⟨hal-03824310⟩
  • Alexandra Bayer Wildberger, Natalia Pinzon, Axel You, Frédérique Truffault, Aurélien Corneau, et al.. Conditioned Mesenchymal Stromal Cells as tools for immunomodulation in Myasthenia Gravis. 14th international MGFA Conference on Myasthenia and Related Disorders, May 2022, Miami, United States. ⟨hal-03824297⟩
  • Sonia Berrih-Aknin. Biomarker response to thymectomy. 14th MGFA International Conference On Myasthenia And Related Disorders, May 2022, Miami (FL), United States. ⟨hal-04008400⟩
  • Rozen Le Panse. Role of endogenous nucleic acids in interferon type 1 signature in early-onset AChR Myasthenia Gravis. 14th MGFA International Conference On Myasthenia And Related Disorders, May 2022, Miami (FL), United States. ⟨hal-04008218⟩
  • Jose Adolfo Villegas, Nadine Dragin. Blocking IL-23 ameliorates Myasthenia Gravis. 14th MGFA International Conference On Myasthenia And Related Disorders, May 2022, Miami, United States. ⟨hal-03844191⟩
  • Jose Adolfo Villegas, Sonia Berrih-Aknin, Rozen Le Panse, Nadine Dragin. Monoclonal antibody anti -IL-23 ameliorates neuromuscular defects in Myasthenia Gravis mouse model. 15th ISNI ( International Society of Neuroimmunology ) Congress, Nov 2021, virtual, France. ⟨hal-03844130⟩
  • Alexandra Bayer Wildberger, Natalia Pinzon, Axel You, Frédérique Truffault, Aurélien Corneau, et al.. Conditioned Mesenchymal Stromal Cells as tools for immunomodulation in Myasthenia Gravis. 15th Congress of the International Society of NeuroImmunology, Nov 2021, Virtual congress, France. ⟨hal-03440270⟩
  • Jose Adolfo Villegas, Sonia Berrih-Aknin, Rozen Le Panse, Nadine Dragin. Blocking the IL-23/Th17 pathway ameliorates myasthenia gravis symptoms in autoimmune myasthenia gravis mouse model. 12th international congress on autoimmunity, May 2021, virtual, France. ⟨hal-03844107⟩
  • Rozen Le Panse. Etiological and Pathophysiological Mechanisms in Myasthenia Gravis. 15th International Congress of Neuroimmunology (ISNI), 2021, Nice (Virtual), France. ⟨hal-03861666⟩
  • Rozen Le Panse. Early onset and Juvenile Myasthenia Gravis. 16th International Congress on Neuromuscular Diseases (ICNMD 2021), 2021, Valencia (Virtual), Spain. ⟨hal-03861656⟩
  • Cloé Payet. Study of interferon type I signature in autoimmune Myasthenia Gravis. 12th International Congress on Autoimmunity, 2021, Athènes (Virtual), Greece. ⟨hal-03861863⟩
  • Jose Adolfo Villegas, Jérôme van Wassenhove, Alexandra Clarissa Bayer Wildberger, Régine Roussin, Nicola Santelmo, et al.. TH17/IL-23 TARGETED THERAPY IN A HUMANIZED MOUSE MODEL OF MYASTHENIA GRAVIS. Autoimmunity 2018, May 2018, Lisbone, Portugal. ⟨hal-03843470⟩
  • Jose Adolfo Villegas, Alexandra Clarissa Bayer Wildberger, Rozen Le Panse, Sonia Berrih-Aknin, Nadine Dragin. IMPLICATION OF INTERLEUKIN 23 IN THE INFLAMMATORY EVENT OCCURING IN MYASTHENIA GRAVIS THYMUS. Autoimmunity 2018, May 2018, Lisbonne, Portugal. ⟨hal-03843507⟩
  • Sonia Berrih-Aknin, Rozen Le Panse, Nadine Dragin. AIRE: a missing link to explain female susceptibility to autoimmune diseases. Experimental biology, Apr 2018, San Diego, United States. ⟨hal-03843571⟩
  • Mélanie Cron. Analysis of microRNA expression in the thymus of Myasthenia Gravis patients opens new research avenues. 11th International Congress on Autoimmunity, 2018, Lisbonne, Portugal. ⟨hal-03861707⟩
  • Rozen Le Panse. ALTERED NUMBER AND FUNCTIONALITY OF REGULATORY B CELLS IN MYASTHENIA GRAVIS PATIENTS.. 11th International Congress on Autoimmunity, 2018, Lisbonne, Portugal. ⟨hal-03861712⟩
  • Nadine Dragin, Geraldine Cizeron-Clairac, Jacky Bismuth, Rozen Le Panse, Sonia Berrih-Aknin. Estrogen-mediated downregulation of AIRE influences the gender-bias in autoimmune diseases. 13th International Conference on Myasthenia Gravis and Related Disorders, May 2017, New-york, United States. ⟨hal-03842819⟩
  • Jose Adolfo Villegas, Rozen Le Panse, Sonia Berrih-Aknin, Nadine Dragin. Interleukin-23 Deregulation Contributes To Thymic Inflammation In Myasthenia Gravis Patients. 13th International Conference on Myasthenia Gravis and Related Disorders, May 2017, New-york, United States. ⟨hal-03842834⟩
  • Marieke Robinet, Bérengère Villeret, Solène Maillard, Mélanie Cron, Sonia Berrih-Aknin, et al.. Toll-like Receptor Agonists to Induce Experimental Autoimmune Myasthenia Gravis. 13th International Conference on Myasthenia Gravis and Related Disorders, 2017, New York, United States. ⟨hal-03861806⟩
  • Sonia Berrih-Aknin, Rozen Le Panse, Nadine Dragin. AIRE: a missing link to explain female susceptibility to autoimmune diseases. 13th International Conference on Myasthenia Gravis and Related Disorders, 2017, New York, United States. pp.21-32, ⟨10.1111/nyas.13529⟩. ⟨hal-02390914⟩
  • Rozen Le Panse. Thymus Involvement in Myasthenia Gravis. 13th International Conference on Myasthenia Gravis and Related Disorders, 2017, New York, United States. ⟨hal-03861799⟩
  • Mélanie A Cron, Solène Maillard, José Villegas, Frédérique Truffault, Muriel Sudres, et al.. Thymus involvement in early-onset myasthenia gravis. 13th International Conference on Myasthenia Gravis and Related Disorders, 2017, New York, United States. pp.137-145, ⟨10.1111/nyas.13519⟩. ⟨hal-01789833⟩
  • Christophe Praud, K. Vauchez, Pascal Zongo, Marc Fiszman, J.T. Vilquin. Kinetics yield and fate of human myoblast implantation into immunodeficient SCID mice. 4th International Congress of Myology, May 2011, Lille, France. ⟨hal-02746393⟩

Poster de conférence35 document

  • Alexandra Bayer Wildberger, Cinthia Bergman, Natalia Pinzon, Axel You, Frédérique Truffault, et al.. Immunomodulation capacities of conditioned mesenchymal stromal cells: benefits and mechanisms in an experimental cell therapy approach for Myasthenia gravis. 7th International Myology Congress, Sep 2022, Nice, France. ⟨hal-03824304⟩
  • Anne-Charlotte Lefranc, Samy Hamadache, Lucie Garnier, Frédérique Truffault, Elie Fadel, et al.. MAY IL-17 PLAY A ROLE IN SKELETAL MUSCLE IN PATHOPHYSIOLOGICAL MECHANISM IN AUTOIMMUNE MG?. 14th MGFA International Conference On Myasthenia And Related Disorders, May 2022, Miami, United States. ⟨hal-03844178⟩
  • Frédérique Truffault, Jérôme van Wassenhove, Elie Fadel, Francis Bolgert, Sophie Demeret, et al.. Novel biomarkers associated with autoimmune Myasthenia Gravis: a pilot study using two different proteomic approaches. 14th MGFA International Conference On Myasthenia And Related Disorders, May 2022, Miami, United States. ⟨hal-03853740⟩
  • Edouard Hemery, Frédérique Truffault, Julien Verdier, Sophie Demeret, Sonia Berrih-Aknin, et al.. Decrease in non-classical monocytes in Myasthenia Gravis patients. 14th MGFA International Conference On Myasthenia And Related Disorders, May 2022, Miami, United States. ⟨hal-03853647⟩
  • Julien Verdier, Edouard Hemery, Odessa-Maud Fayet, Frédérique Truffault, Aurélien Corneau, et al.. Characterization of circulating immune cells in Myasthenia Gravis by mass cytometry revealed dysregulation on innate immune cells. 14th MGFA International Conference On Myasthenia And Related Disorders, May 2022, Miami, United States. ⟨hal-03853709⟩
  • Halliez Marius, Cottin Steve, You Axel, Lemaitre Mégane, Ezan Jérome, et al.. MUSK CYSTEIN RICH DOMAIN IN AUTOIMMUNE MYASTHENIC SYNDROME. 14th MGFA International Conference On Myasthenia And Related Disorders, 2022, Miami (Florida), United States. ⟨hal-04002779⟩
  • Frédérique Truffault, Axel You, Julien Verdier, Sophie Demeret, Rozen Le Panse, et al.. Decrease in non-classical monocytes in Myasthenia Gravis patients. Congrès annuel de la Société Française d’Immunologie, 2022, Nice, France. ⟨hal-03861651⟩
  • Halliez Marius, Cottin Steve, You Axel, Lemaitre Mégane, Ezan Jérome, et al.. MUSK CYSTEIN RICH DOMAIN IN AUTOIMMUNE MYASTHENIC SYNDROME. 7th International Myology Congress, 2022, Nice, France. ⟨hal-04002800⟩
  • Axel You, Odessa-Maud Fayet, Solene Maillard, Laureline Bétemps, Nadine Dragin, et al.. Development of a new experimental Myasthenia Gravis mouse model.. MYOLOGY 2022, 2022, Nice, France. ⟨hal-03861640⟩
  • Anne-Charlotte Lefranc, Samy Hamadache, Charles Grosjean, Nadine Dragin. IL-17, SKELETAL MUSCLE AND MYASTHENIA GRAVIS. SFI 2021, Dec 2021, Paris, France. ⟨hal-03844152⟩
  • Judith Merrheim, Sonia Berrih-Aknin, Rozen Le Panse, Nadine Dragin. AhR ligands effects on thymic epithelial cell differentiation and function. 12th international congress on autoimmunity, May 2021, virtual, France. ⟨hal-03844091⟩
  • Alexandra Bayer Wildberger, José Villegas, Julien Verdier, Mariette Giannini, Solène Maillard, et al.. Will Mesenchymal Stromal Cells become tools for immunomodulation in Myasthenia Gravis ?. 12th International Congress on Autoimmunity, May 2021, Virtual Congress, Greece. ⟨hal-03440251⟩
  • Claire Lefeuvre, Cloé Payet, Odessa-Maud Fayet, Solène Maillard, Frédérique Truffault, et al.. Risk factors associated with myasthenia gravis in thymoma patients: a link with ectopic germinal centers. 12th International Congress on Autoimmunity, 2021, Athènes (Virtual), Greece. ⟨hal-03861873⟩
  • Frédérique Truffault, Jérôme van Wassenhove, Elie Fadel, Francis Bolgert, Sophie Demeret, et al.. Altered Novel biomarkers associated with autoimmune Myasthenia Gravis: a pilot study using two different proteomic approaches. 15th International Congress of Neuroimmunology (ISNI), 2021, Nice (Virtual), France. ⟨hal-03861685⟩
  • Jessy Etienne, Pierre Joanne, Cyril Catelain, Stéphanie Riveron, Alexandra Clarissa Bayer, et al.. Targeting aldehyde dehydrogenase to mitigate the physiopathology of Duchenne muscular dystrophy. 3rd Victorian Muscle Network Symposium 2020, Oct 2020, Virtual Congress, Australia. ⟨hal-03440309⟩
  • Guotian Luo, Joseph Paquet, Julie Boisselier, Adeline Gand, Adrien Moya, et al.. Enzyme-controlled, Nutritive Hydrogel For Mesenchymal Stem Cell Survival And Paracrine Functions. Orthopaedic Research Society, Feb 2020, Phenix, United States. ⟨hal-02365029⟩
  • Jose Adolfo Villegas, Jerôme van Wassenhove, Judith Merrheim, Karen Matta, Frédérique Truffault, et al.. Beneficial effects of blocking the IL-23/Th17 pathway in a humanized preclinical MG model. sfi 2019, Nov 2019, Nantes, France. ⟨hal-03843606⟩
  • Alexandra Bayer Wildberger, José Villegas, Julien Verdier, Mariette Giannini, Solène Maillard, et al.. Phenotypical and functional characterizations of conditioned Mesenchymal Stromal Cells MSC, as tools for immunomodulation in Myasthenia Gravis. 52ème Meeting de la Société Française d'Immunologie, Nov 2019, Nantes, France. ⟨hal-03038636⟩
  • Judith Merrheim, Jérôme van Wassenhove, Bastien Ducreux, Régine Roussin, Sonia Berrih-Aknin, et al.. Effect of AhR ligands on thymic epithelial cell differentiation and function. SFI 2019, Nov 2019, Nantes, France. ⟨hal-03843650⟩
  • Maximilien Sochala, Raphaël Porcher, Tanya Stojkovic, Henri Marc Bécane, Anthony Béhin, et al.. High Risk of Fatal and Non-Fatal Venous Thromboembolism in Myotonic Dystrophy. 6th International Congress of Myology, Mar 2019, Bordeaux, France. ⟨hal-04020135⟩
  • Jessy Etienne, Pierre Joanne, Alexandra Bayer, Cyril Catelain, Stéphanie Riveron, et al.. Characterization of aldehyde dehydrogenase isoenzymes in Man, Macaque and Dog skeletal muscles. Myology 2019, Mar 2019, Bordeaux, France. ⟨hal-02364988⟩
  • Alexandra Bayer Wildberger, Solène Maillard, Julien Verdier, José Villegas, Frédérique Truffault, et al.. Mesenchymal Stromal Cells (MSC) : phenotypical and functional characterizations as tools for immunomodulation in Myasthenia Gravis. Myology 2019, Mar 2019, Bordeaux, France. ⟨hal-02364999⟩
  • Julien Verdier, Frédérique Truffault, Anthony Behin, Catherine Blanc, Rozen Le Panse, et al.. Characterization of circulating immune cells in a rare autoimmune disease: Myasthenia gravis. Annual Meeting of the French Society for Immunology, 2019, Nantes, France. ⟨hal-03861850⟩
  • Cloé Payet, Frédérique Truffault, Claire Lefeuvre, Vincent Bondet, Darragh Duffy, et al.. Study of interferon type I signature in myasthenia gravis. EMBO Workshop - Cell death in immunity and inflammation, 2019, Crète, Greece. ⟨hal-03861828⟩
  • Cloé Payet, Frédérique Truffault, Claire Lefeuvre, Vincent Bondet, Darragh Duffy, et al.. Study of interferon type I signature in myasthenia gravis. Annual Meeting of the French Society for Immunology, 2019, Nantes, France. ⟨hal-03879620⟩
  • José Adolfo Villegas, Rémi Khansa, Jerôme van Wassenhove, Katia Ider, Régine Roussin, et al.. AhR activation in thymic epithelial cells can modify immune tolerance process. Autoimmunity 2018, May 2018, Lisbonne, Portugal. ⟨hal-03843522⟩
  • Julien Verdier, Frédérique Truffault, Bruno Eymard, Catherine Blanc, Rozen Le Panse, et al.. Characterization of circulating immune cells in Myasthenia gravis using mass cytometry. MYOLOGY 2018, 2018, Bordeaux, France. ⟨hal-03861860⟩
  • Mélanie Cron, Solène Maillard, Frédérique Truffault, Ambra Vittoria Gualeni, Annunziata Gloghini, et al.. Role of miR-150 in autoimmune Myasthenia Gravis. 11th International Congress on Autoimmunity, 2018, Lisbonne, Portugal. ⟨hal-03861704⟩
  • Julien Verdier, Frédérique Truffault, Bruno Eymard, Catherine Blanc, Aurélien Corneau, et al.. Characterization of circulating immune cells in a rare autoimmune disease: Myasthenia gravis. Single Cell Symposium, 2018, Paris, France. ⟨hal-03861844⟩
  • Julien Verdier, Frédérique Truffault, Bruno Eymard, Rozen Le Panse, Sonia Berrih-Aknin. Characterization of circulating immune cells in a rare autoimmune disease: Myasthenia gravis. Congrès Annuel de l'AFC - Cytométrie 2018, 2018, Lyon, France. ⟨hal-03861835⟩
  • Jose Adolfo Villegas, Katia Ider Bsc, Alexandra Clarissa Bayer Wildberger, Rozen Le Panse, Sonia Berrih-Aknin, et al.. IMPLICATION OF INTERLEUKIN 23 IN THE INFLAMMATORY EVENT OCCURING IN MYASTHENIA GRAVIS THYMUS. ESID Focus Meeting “Autoimmunity & Inflammation in PID; Beyond the Paradox, Sep 2017, edinburgh, United Kingdom. ⟨hal-03843484⟩
  • Rémi Khansa, Jose Adolfo Villegas, Rozen Le Panse, Sonia Berrih-Aknin, Nadine Dragin. AhR activation may regulate expression of pro-inflammatory factors in thymuses of AChR+ Myasthenia Gravis patients.. 13th International Conference on Myasthenia Gravis and Related Disorders, May 2017, New-York, United States. ⟨hal-03842770⟩
  • Mélanie Cron, Solène Maillard, Frédérique Truffault, Ambra Vittoria Gualeni, Annunziata Gloghini, et al.. Role of miR-150 in autoimmune Myasthenia Gravis. 13th International Conference on Myasthenia Gravis and Related Disorders, 2017, New York, United States. ⟨hal-03861811⟩
  • Vuslat Yilmaz, Solène Maillard, Frédérique Truffault, Bruno Eymard, Jean François Regnard, et al.. Altered Number and Functionality of Regulatory B Cells in Myasthenia Gravis Patients. 13th International Conference on Myasthenia Gravis and Related Disorders, 2017, New York, United States. ⟨hal-03861819⟩
  • Sabrina Sacconi, Jean-Thomas Vilquin, Serge Colson, Jonathan Bocquet, Jacques Darcourt, et al.. A phase I/II clinical trial of autologous myoblast transplantation in facioscapulohumeral muscular dystrophy. Myology 2016, Mar 2016, Lyon, France. ⟨hal-02394504⟩

Chapitres d'ouvrage1 document

  • Linda Kusner, Rozen Le Panse, Mario Losen, William Donald Phillips. Animal models of Myasthenia Gravis for Preclinical Evaluation. Henry J. Kaminski; Linda L. Kusner. Myasthenia Gravis and Related Disorders, Humana Cham, 2018, Myasthenia Gravis and Related Disorders, 978-3-319-73585-6. ⟨10.1007/978-3-319-73585-6⟩. ⟨hal-03861276⟩

Autres publications2 document


Thèses3 document


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