Personnel

Julia Lemos

Post-doctoral researcher

Julia P.Lemos
Email

Titres

PhD; Postdoctoral researcher

Expertises

  • Cellular biology
  • Immunology
  • Immune diseases

Présentation

Holder of a PhD (2018) in cellular and molecular biology with a specialization in immunology at the Oswaldo Cruz Institute (FIOCRUZ-RJ). During my scientific training, my research focused on the characterization of changes in the immune system in the context of various pathologies and infections of global and current importance, such as type 1 diabetes, T-cell lymphoblastic leukemia and lymphoma and ZIKA. Considering the fact that immunotherapy has has recently emerged as a promising modality for the cure of hematological disorders, I continued my research as a postdoctoral researcher at the Saint-Louis Research Institute, based on the generation of new concepts on the interaction between hematopoietic and stromal cells in the bone marrow, essential for the differentiation and specification of lymphoid progenitors. In June 2021, I joined the Myology Research Center in the group led by Dr Piera Smeriglio. My work focuses on the role of the immune system and, more particularly, of the thymus, as a lymphoid organ responsible for the development of T cells, in the pathogenesis of Amyotrophic Lateral Sclerosis.

Principales publications

  1. Abou Nader, Z, Espéli, M, Balabanian, K, P Lemos, J. Culture, Expansion and Differentiation of Mouse Bone-Derived Mesenchymal Stromal Cells. Methods Mol Biol. 2021;2308 :35-46. doi: 10.1007/978-1-0716-1425-9_3. PubMed PMID:34057712 .
  2. Bonaud, A, Lemos, JP, Espéli, M, Balabanian, K. Hematopoietic Multipotent Progenitors and Plasma Cells: Neighbors or Roommates in the Mouse Bone Marrow Ecosystem?. Front Immunol. 2021;12 :658535. doi: 10.3389/fimmu.2021.658535. PubMed PMID:33936091 PubMed Central PMC8083056.
  3. Messias, CV, Lemos, JP, Cunha, DP, Vasconcelos, Z, Raphael, LMS, Bonaldo, MC et al.. Zika virus infects human blood mononuclear cells. BMC Infect Dis. 2019;19 (1):986. doi: 10.1186/s12879-019-4622-y. PubMed PMID:31752731 PubMed Central PMC6873492.
  4. Lemos, JP, Smaniotto, S, Messias, CV, Moreira, OC, Cotta-de-Almeida, V, Dardenne, M et al.. Sphingosine-1-Phosphate Receptor 1 Is Involved in Non-Obese Diabetic Mouse Thymocyte Migration Disorders. Int J Mol Sci. 2018;19 (5):. doi: 10.3390/ijms19051446. PubMed PMID:29757216 PubMed Central PMC5983610.
  5. Messias, CV, Santana-Van-Vliet, E, Lemos, JP, Moreira, OC, Cotta-de-Almeida, V, Savino, W et al.. Sphingosine-1-Phosphate Induces Dose-Dependent Chemotaxis or Fugetaxis of T-ALL Blasts through S1P1 Activation. PLoS One. 2016;11 (1):e0148137. doi: 10.1371/journal.pone.0148137. PubMed PMID:26824863 PubMed Central PMC4732661.
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